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Ulrike Holzgrabe
Researcher at University of Würzburg
Publications - 591
Citations - 11158
Ulrike Holzgrabe is an academic researcher from University of Würzburg. The author has contributed to research in topics: Allosteric regulation & Capillary electrophoresis. The author has an hindex of 45, co-authored 566 publications receiving 9806 citations. Previous affiliations of Ulrike Holzgrabe include Jagiellonian University & University of Illinois at Chicago.
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Journal ArticleDOI
Enhanced Fluorescence Resonance Energy Transfer in G-Protein-Coupled Receptor Probes on Nanocoated Microscopy Coverslips
Benjamin Schreiber,Michael Kauk,Michael Kauk,Hannah S. Heil,Monika Emmerling,Ingrid Tessmer,Martin Kamp,Sven Höfling,Sven Höfling,Ulrike Holzgrabe,Carsten Hoffmann,Carsten Hoffmann,Katrin G. Heinze +12 more
TL;DR: It is shown that gold-coated glass coverslips reinforce the otherwise forbidden donor–acceptor energy transfer by virtual optimization of the dipole orientation and the resulting enhanced FRET efficiency is confirmed on nanocoatings for the inactive M1 muscarinic acetylcholine receptor (mAChR) labeled with a FRE...
Journal ArticleDOI
Indoles XIV. 4-Phenylpyrido[4,3-b]indoles and 5-Phenylazepino[4,5-b]indoles by Cyclisation of N-Indolylalkyl-ephedrine Derivatives — Scope and Stereoselectivity
Journal ArticleDOI
Kappa-receptor selective binding of opioid ligands with a heterocyclic bicyclo[3.3.1]nonan-9-one structure.
TL;DR: It was shown by molecular modelling that heterocyclic bicyclo[3.3.1]nonan-9-ones fit very well with the structure of ketazocine, a prototypic kappa-selective benzomorphan compound; when compared to the arylacetamide structure of U-69, a specific kappa1-receptor agonist, a similar geometry was found with a slightly different distribution of the charges.
Book ChapterDOI
11 The need for CE methods in pharmacopoeial monographs
TL;DR: Methods and perspectives for new applications for capillary electrophoresis methods, currently applied in the European and the United States pharmacopoeias, are given.
Journal ArticleDOI
Serjanic Acid Improves Immunometabolic Markers in a Diet-Induced Obesity Mouse Model.
Gustavo Gutiérrez,Deisy Giraldo-Dávila,Marianny Y. Combariza,Ulrike Holzgrabe,Jorge H. Tabares-Guevara,José R. Ramírez-Pineda,Sergio Acín,Diana L. Muñoz,Guillermo Montoya,Norman Balcazar +9 more
TL;DR: The study aimed to isolate serjanic acid and evaluate its effect in a prediabetic murine model by oral administration, and found the reduction of inflammation markers related to adipocyte differentiation is reported.