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Ulrike Holzgrabe
Researcher at University of Würzburg
Publications - 591
Citations - 11158
Ulrike Holzgrabe is an academic researcher from University of Würzburg. The author has contributed to research in topics: Allosteric regulation & Capillary electrophoresis. The author has an hindex of 45, co-authored 566 publications receiving 9806 citations. Previous affiliations of Ulrike Holzgrabe include Jagiellonian University & University of Illinois at Chicago.
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Journal ArticleDOI
Reductions of 3,11-Dipyridyl-Substituted 5-Oxo-2,6-methano-6-benz(c)azocine Carboxylates.
Journal ArticleDOI
5α-Reduktase-Inhibitoren – Benigne Prostatahyperplasie und vieles mehr. BPH, Alopezie und Co.
Ulrike Holzgrabe,Edith Bennack +1 more
TL;DR: The 5α-Reduktase-Inhibitoren Finasterid und Dutasterid konnen bei der BPH gleichwertig eingesetzt werden as mentioned in this paper.
Journal ArticleDOI
A Sequence of Aldol Condensations and a Michael Addition Giving a Cyclohexenone Ring System.
Ulrich Kuhl,Ulrike Holzgrabe +1 more
TL;DR: In this paper, the reaction of 1,5-diphenylpentanetrione, 4-chlorobenzaldehyde, and acetone in the presence of methylamine resulted in 2,6-dibenzoyl-5-(4-chlorphenyl)-3-methyl-cyclohex-2-en-1-one, which was formed by a sequence of a Knoevenagel reaction, an aldol condensation, and a Michael addition in a one-pot reaction.
Posted ContentDOI
Mouse model for testing SARS-CoV-2 antivirals: Pharmacokinetics
Oliver Scherf-Clavel,Martina Kinzig,Bettina Friedl,Edith Kaczmarek,Malte Feja,Manuela Gernert,Franziska Richter,Rainer Höhl,Roland Nau,Ulrike Holzgrabe,Fritz Sörgel +10 more
TL;DR: The mouse model was able to characterise the PK and tissue distribution of both model substances and is a suitable tool to investigate early drug candidates against SARS-CoV-2.
Journal ArticleDOI
Bitopic muscarinic agonists and antagonists and uses thereof: a patent evaluation of US20160136145A1.
Ulrike Holzgrabe,Michael Decker +1 more
TL;DR: The quaternary amine structure of the compounds claimed will prohibit penetration into the CNS and their ester structure will lead to significant metabolic instability which will hamper therapeutic applications for many indications.