V
Victor Abler
Researcher at ACADIA Pharmaceuticals Inc.
Publications - 42
Citations - 395
Victor Abler is an academic researcher from ACADIA Pharmaceuticals Inc.. The author has contributed to research in topics: Dementia & Medicine. The author has an hindex of 9, co-authored 32 publications receiving 208 citations.
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Journal ArticleDOI
Dopamine D2 receptor gene variants and response to rasagiline in early Parkinson's disease: a pharmacogenetic study
Mario Masellis,Shannon Collinson,Natalie Freeman,Maria Tampakeras,Joseph Levy,Amir Tchelet,Eli Eyal,Elijahu Berkovich,Rom E. Eliaz,Victor Abler,Iris Grossman,Cheryl Fitzer-Attas,Arun K. Tiwari,Michael R. Hayden,James L. Kennedy,Anthony E. Lang,Jo Knight,Adagio investigators +17 more
TL;DR: A clinically meaningful benefit to rasagiline is indicated in terms of the magnitude of improvement in parkinsonian symptoms for those with the favourable response genotypes.
Journal ArticleDOI
Long-term effects of rasagiline and the natural history of treated Parkinson's disease.
Olivier Rascol,Robert A. Hauser,Fabrizio Stocchi,Cheryl Fitzer-Attas,Yulia Sidi,Victor Abler,C. Warren Olanow +6 more
TL;DR: This follow-up study aimed to assess whether benefits of early‐start treatment with rasagiline 1 mg/day versus delayed‐ start treatment in PD persist and the clinical progression rate during long‐term naturalistic treatment.
Journal ArticleDOI
Challenges and opportunities for improving the landscape for Lewy body dementia clinical trials.
Jennifer G. Goldman,Leah K. Forsberg,Bradley F. Boeve,Melissa J. Armstrong,David J. Irwin,Tanis J. Ferman,Doug R. Galasko,James E. Galvin,Daniel I. Kaufer,James B. Leverenz,Carol F. Lippa,Karen Marder,Victor Abler,Kevin Biglan,Michael C. Irizarry,Bill Keller,Leanne Munsie,Masaki Nakagawa,Angela C. Taylor,Todd Graham +19 more
TL;DR: There are opportunities to improve the landscape of LBD clinical trials by harmonizing clinical assessments and biomarkers across cohorts and research studies, developing and validating outcome measures in LBD, engaging the patient community to assess research needs and priorities, and incorporating biomarker and genotype profiling in study design.
Journal ArticleDOI
Recommendations of the Global Multiple System Atrophy Research Roadmap Meeting
Ryan R. Walsh,Florian Krismer,Wendy R Galpern,Wendy R Galpern,Gregor K. Wenning,Phillip A. Low,Glenda M. Halliday,Glenda M. Halliday,Walter J. Koroshetz,Janice L. Holton,Niall Quinn,Olivier Rascol,Leslie M. Shaw,David Eidelberg,Pam Bower,Jeffrey L. Cummings,Victor Abler,Judy Biedenharn,Gal Bitan,David J. Brooks,Patrik Brundin,Hubert H. Fernandez,Philip Fortier,Roy Freeman,Thomas Gasser,Thomas Gasser,Art Hewitt,Günter U. Höglinger,Günter U. Höglinger,Matthew J. Huentelman,Poul Henning Jensen,Andreas Jeromin,Un Jung Kang,Horacio Kaufmann,Lawrence Kellerman,Vikram Khurana,Vikram Khurana,Thomas Klockgether,Thomas Klockgether,Woojin S. Kim,Carol Langer,Peter A. LeWitt,Peter A. LeWitt,Eliezer Masliah,Wassilios G. Meissner,Ronald Melki,Susanne Ostrowitzki,Steven Piantadosi,Werner Poewe,David Robertson,Cyndi Roemer,Dale Schenk,Michael G. Schlossmacher,Jeremy D. Schmahmann,Klaus Seppi,Lily Shih,A. Siderowf,Glenn T. Stebbins,Nadia Stefanova,Shoji Tsuji,Sharon Sutton,Jing Zhang +61 more
TL;DR: An international meeting involving leaders in the field and MSA advocacy groups was convened in Las Vegas, Nevada, to identify critical research areas where consensus and progress was needed to improve understanding, diagnosis, and treatment of the disease.
Journal ArticleDOI
Tardive dyskinesia among patients using antipsychotic medications in customary clinical care in the United States.
TL;DR: Despite a lower TD prevalence than previously estimated and the predominant use of atypical antipsychotics, identified TD patients appear to have a substantial comorbidity burden that requires special treatment and management consideration.