V
Vineet Gupta
Researcher at University of Miami
Publications - 183
Citations - 5600
Vineet Gupta is an academic researcher from University of Miami. The author has contributed to research in topics: Pancreatic cancer & Integrin alpha M. The author has an hindex of 32, co-authored 158 publications receiving 4506 citations. Previous affiliations of Vineet Gupta include Rush University Medical Center & University of Minnesota.
Papers
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Journal ArticleDOI
Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis
Changli Wei,Shafic El Hindi,Jing Li,Alessia Fornoni,Nelson Goes,Junichiro Sageshima,Dony Maiguel,S. Ananth Karumanchi,Hui-Kim Yap,Moin A. Saleem,Qing-Yin Zhang,Boris Nikolic,Abanti Chaudhuri,Pirouz Daftarian,Eduardo Salido,Armando Torres,Moro O. Salifu,Minnie M. Sarwal,Franz Schaefer,Christian Morath,Vedat Schwenger,Martin Zeier,Vineet Gupta,David M. Roth,Maria Pia Rastaldi,George W. Burke,Phillip Ruiz,Jochen Reiser +27 more
TL;DR: It is reported that serum soluble urokinase receptor (suPAR) is elevated in two-thirds of subjects with primary FSGS, but not in people with other glomerular diseases, and that a higher concentration of suPAR before transplantation underlies an increased risk for recurrence of FSGS after transplantation.
Journal ArticleDOI
Modification of kidney barrier function by the urokinase receptor
Changli Wei,Clemens C. Möller,Mehmet M. Altintas,Jing Li,Karin Schwarz,Serena Zacchigna,Liang Xie,Anna Henger,Holger Schmid,Maria Pia Rastaldi,Peter J. Cowan,Matthias Kretzler,Roberto L. Parrilla,Moise Bendayan,Vineet Gupta,Boris Nikolic,Raghu Kalluri,Peter Carmeliet,Peter Mundel,Jonche Reiser +19 more
TL;DR: It is shown that induction of urokinase receptor (uPAR) signaling in podocytes leads to foot process effacement and urinary protein loss via a mechanism that includes lipid-dependent activation of αvβ3 integrin.
Journal ArticleDOI
Abatacept in B7-1–Positive Proteinuric Kidney Disease
Chih Chuan Yu,Chih Chuan Yu,Alessia Fornoni,Astrid Weins,Samy Hakroush,Dony Maiguel,Junichiro Sageshima,Linda Chen,Gaetano Ciancio,Mohd Hafeez Faridi,Daniel Behr,Kirk N. Campbell,Jer Ming Chang,Hung Chun Chen,Jun Oh,Christian Faul,M. Amin Arnaout,Paolo Fiorina,Vineet Gupta,Anna Greka,George W. Burke,Peter Mundel +21 more
TL;DR: Data indicate that abatacept may stabilize β1-integrin activation in podocytes and reduce proteinuria in patients with B7-1-positive glomerular disease.
Patent
Clinically intelligent diagnostic devices and methods
TL;DR: In this paper, the authors describe the use of microarrays for differential diagnosis of specific clinical symptoms or sets of symptoms, based on known clinical presentations of symptoms associated with specific diseases and disorders.
Journal ArticleDOI
Integrin CD11b activation drives anti-tumor innate immunity.
Michael C. Schmid,Samia Q. Khan,Megan M. Kaneda,Paulina Pathria,Ryan M. Shepard,Tiani L. Louis,Sudarshan Anand,Gyunghwi Woo,Chris Leem,M. Hafeez Faridi,Terese Geraghty,Anugraha Rajagopalan,Seema Gupta,Mansoor M. Ahmed,Roberto I. Vazquez-Padron,David A. Cheresh,Vineet Gupta,Judith A. Varner +17 more
TL;DR: In the tumor microenvironment, CD 11b is not essential for recruitment of myeloid cells but rather induces macrophage anti-tumorigenic polarization via stimulating let7a and NFκB signaling and that pharmacological activation of CD11b enhances survival in mouse models of cancer.