Visanu Thamlikitkul

TL;DR: Model-fitted parameter estimates were used to derive suggested loading and maintenance dosing regimens for various categories of patients, including those on hemodialysis and continuous renal replacement, and colistin may best be used as part of a highly active combination.

TL;DR: In this paper, the authors report consensus therapeutic guidelines for agent selection and dosing of colistin and polymyxin antibiotics for optimal use in adult patients, as endorsed by the American College of Clinical Pharmacy (ACCP), Infectious Diseases Society of America (IDSA), International Society of Anti-Infective Pharmacology (ISAP), Society for Critical Care Medicine (SCCM), and Society of Infectious diseases Pharmacists (SIDP).

TL;DR: It is confirmed that MRSA infections in the community have been increasing in Asian countries and data suggest that various MRSA clones have spread between the community and hospitals as well as between countries.

TL;DR: The most remarkable findings about the epidemiology of S. pneumoniae in Asian countries after the introduction of PCV7 were the high prevalence of macrolide resistance and MDR and distinctive increases in serotype 19A.

TL;DR: These isolates are highly resistant to major antimicrobial agents, which could limit the therapeutic options in the clinical practice and significantly increases the likelihood of pneumonia-related mortality.