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Walter Berger
Researcher at Medical University of Vienna
Publications - 396
Citations - 16667
Walter Berger is an academic researcher from Medical University of Vienna. The author has contributed to research in topics: Cancer & Cell culture. The author has an hindex of 63, co-authored 359 publications receiving 14045 citations. Previous affiliations of Walter Berger include University of Vienna & Université libre de Bruxelles.
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Journal ArticleDOI
The sodium pump α1 sub-unit: a disease progression–related target for metastatic melanoma treatment
Véronique Mathieu,Christine Pirker,Elisabeth Martin de Lassalle,Mathieu Vernier,Tatjana Mijatovic,Nancy Deneve,Jean-François Gaussin,Mischaël Dehoux,Florence Lefranc,Walter Berger,Robert Kiss +10 more
TL;DR: The data show that all investigated human melanoma cell lines expressed high levels of the α1 sub‐unit, and 33% of human melanomas displayed significant α1Sub‐unit expression in correlation with the Breslow index, and cardenolides (notably UNBS1450; currently in Phase I clinical trials) displayed marked anti‐tumour effects against melanomas in vitro.
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Fibroblast growth factor receptor-mediated signals contribute to the malignant phenotype of non-small cell lung cancer cells: therapeutic implications and synergism with epidermal growth factor receptor inhibition
Hendrik Fischer,Ninon Taylor,Sigrid Allerstorfer,Michael Grusch,Gudrun Sonvilla,Klaus Holzmann,Ulrike Setinek,Leonilla Elbling,Heidelinde Cantonati,Bettina Grasl-Kraupp,Christine Gauglhofer,Brigitte Marian,Michael Micksche,Walter Berger +13 more
TL;DR: FGFR-mediated signals in cooperation with those transmitted by epidermal growth factor receptor are involved in growth and survival of human NSCLC cells and should be considered as targets for combined therapeutic approaches.
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Up‐regulation of the fibroblast growth factor 8 subfamily in human hepatocellular carcinoma for cell survival and neoangiogenesis
Christine Gauglhofer,Sandra Sagmeister,Waltraud C. Schrottmaier,Carina Fischer,Chantal Rodgarkia-Dara,Thomas Mohr,Stefan Stättner,Christoph Bichler,Daniela Kandioler,Fritz Wrba,Rolf Schulte-Hermann,Klaus Holzmann,Michael Grusch,Brigitte Marian,Walter Berger,Bettina Grasl-Kraupp +15 more
TL;DR: FGF8, FGF17, and FGF18 are involved in autocrine and paracrine signaling in HCC and enhance the survival of tumor cells under stress conditions, malignant behavior, and neoangiogenesis.
Journal ArticleDOI
Expression of the major vault protein LRP in human non-small-cell lung cancer cells: activation by short-term exposure to antineoplastic drugs.
TL;DR: A role of vaults is suggested both in basic CDDP resistance and, additionally, in an short‐term defensive response of NSCLC cells against several other drugs.
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Evidence for a role of FGF-2 and FGF receptors in the proliferation of non-small cell lung cancer cells.
Walter Berger,Ulrike Setinek,Thomas Mohr,Ingela Kindås-Mügge,Monika Vetterlein,Gerhard Dekan,F. Eckersberger,Carlos Caldas,Michael Micksche +8 more
TL;DR: A role of FGF‐2 and FGFR in the growth stimulation of NSCLC cells possibly via an intracrine mechanism is suggested.