W
Walter Berger
Researcher at Medical University of Vienna
Publications - 396
Citations - 16667
Walter Berger is an academic researcher from Medical University of Vienna. The author has contributed to research in topics: Cancer & Cell culture. The author has an hindex of 63, co-authored 359 publications receiving 14045 citations. Previous affiliations of Walter Berger include University of Vienna & Université libre de Bruxelles.
Papers
More filters
Journal ArticleDOI
Results of the extended analysis for cancer treatment (EXACT) trial: a prospective translational study evaluating individualized treatment regimens in oncology.
Gerald W. Prager,Matthias Unseld,Fredrik Waneck,Robert M. Mader,Fritz Wrba,Markus Raderer,Thorsten Fuereder,Phillip Staber,Ulrich Jäger,Markus Kieler,Daniela Bianconi,Mir Alireza Hoda,Lukas Baumann,Alexander Reinthaller,Walter Berger,Christoph Grimm,Heinz Kölbl,Maria Sibilia,Leonhard Müllauer,Christoph C. Zielinski +19 more
TL;DR: The prospective trial EXACT suggests that treatment based on real-time molecular tumor profiling leads to superior clinical benefit in patients after failure of standard treatment concepts.
Journal ArticleDOI
Altered membrane rigidity via enhanced endogenous cholesterol synthesis drives cancer cell resistance to destruxins.
Daniela Heilos,Daniela Heilos,Clemens Röhrl,Christine Pirker,Bernhard Englinger,Dina Baier,Thomas Mohr,Michaela Schwaiger,Shahid Iqbal,Sushilla van Schoonhoven,Kristaps Klavins,Tanja Eberhart,Ursula Windberger,Judith Taibon,Sonja Sturm,Hermann Stuppner,Gunda Koellensperger,Rita Dornetshuber-Fleiss,Rita Dornetshuber-Fleiss,Walter Jäger,Rosa Lemmens-Gruber,Walter Berger +21 more
TL;DR: A reduced ionophoric activity of destruxins is suggested due to cholesterol-mediated plasma membrane re-organization as molecular mechanism underlying acquired Destruxin resistance in human colon cancer cells.
Journal ArticleDOI
Post-digestion stabilization of osmium enables quantification by ICP-MS in cell culture and tissue
Matthias H. M. Klose,Michaela Hejl,Petra Heffeter,Petra Heffeter,Michael A. Jakupec,Samuel M. Meier-Menches,Walter Berger,Walter Berger,Bernhard K. Keppler +8 more
TL;DR: An orally active osmium anticancer compound was reliably quantified in the organs of treated mice by inductively coupled plasma-mass spectrometry (ICP-MS) by adding a stabilizing solution consisting of ascorbic acid, thiourea and EDTA during sample preparation and avoiding oxidizing conditions.
Journal ArticleDOI
CD44 drives aggressiveness and chemoresistance of a metastatic human osteosarcoma xenograft model
Lisa Mayr,Christine Pirker,Daniela Lötsch,Sushilla van Schoonhoven,Reinhard Windhager,Bernhard Englinger,Walter Berger,Bernd Kubista +7 more
TL;DR: The osteosarcoma xenograft models with increased metastatic potential developed in this study can be useful for identification of mechanisms driving metastasis and resistance towards clinically used and novel therapeutic regimens.
Journal ArticleDOI
Opposing Roles of JNK and p38 in Lymphangiogenesis in Melanoma.
Emmi Puujalka,Magdalena Heinz,Bastian Hoesel,Peter Friedl,Bernhard Schweighofer,Judith Wenzina,Christine Pirker,Johannes A. Schmid,Robert Loewe,Erwin F. Wagner,Walter Berger,Peter Petzelbauer +11 more
TL;DR: VEGF-C and MITF levels serve as surrogate markers for the respective c-Jun N-terminal kinase and p38 activities and may be used to predict the risk of metastasis in primary melanoma.