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Walter Berger

Researcher at Medical University of Vienna

Publications -  396
Citations -  16667

Walter Berger is an academic researcher from Medical University of Vienna. The author has contributed to research in topics: Cancer & Cell culture. The author has an hindex of 63, co-authored 359 publications receiving 14045 citations. Previous affiliations of Walter Berger include University of Vienna & Université libre de Bruxelles.

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Specific antioxidant compounds differentially modulate cytotoxic activity of doxorubicin and cisplatin: in vitro and in vivo study.

TL;DR: Protective effect of specific antioxidant agents during cytotoxic action of doxorubicin was demonstrated in vitro in drug-sensitive human tumor cells and in adult male Wistar rats, while there was no protective effect indrug-resistant sub-lines of these tumor cells during action ofDoxorUBicin and cisplatin.
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Nanoformulations of anticancer FGFR inhibitors with improved therapeutic index.

TL;DR: In an FGFR inhibitor-sensitive murine osteosarcoma transplantation model (K7M2), only liposomal but not free ponatinib resulted in significant tumor growth inhibition (by 60.4%) at markedly reduced side effects.
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Fibroblast growth factor receptor 4 induced resistance to radiation therapy in colorectal cancer.

TL;DR: FGFR4 may serve as a predictive marker to select CRC patients with MMR-proficient tumors who may benefit from pre-operative radiotherapy by analyzing its levels in rectal tumors of patients with different responses to the therapy.
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Impact of CYP24A1 overexpression on growth of colorectal tumour xenografts in mice fed with vitamin D and soy

TL;DR: It is demonstrated that CYP24A1 overexpression results in increased aggressiveness and proliferative potential of colorectal tumours and combination of vitamin D3 and soy could have an anti‐tumourigenic effect only if CYP 24A1 levels are normal.