Walter Berger

TL;DR: In conclusion, TMZ affects the expression and secretion of CXCL2 (and, to a lesser extent, C XCL3 and CXcl8) in glioma cells, and CxCL2 directly impacts gliomas cell biology.

TL;DR: In this article, the in vitro growth inhibitory effects of seven cardiac glycosides including five cardenolides (ouabain, digoxin, digitoxin, gitoxin, uzarigenin-rhamnoside, and their respective aglycone forms) and two bufadienolides were determined by means of the MTT colorimetric assay and hellebrigenin induced cytotoxic effects were visualized by using quantitative videomicroscopy.

TL;DR: Overexpression of the small heat shock protein Hsp27 is shown to inhibit the in vitro proliferation rate and to delay tumor development of a human melanoma cell line (A375) in nude mice and to influence the neoplastic phenotype.

TL;DR: Three Pt molecular squares of distinct size show biological activity against cancer cells and heavily influence the expression of genes known to form G-quadruplexes in their promoter regions.

TL;DR: The use of liquid chromatography in combination with inductively coupled plasma mass spectrometry (LC-ICP-MS) enabled accurate intact cisplatin quantification in cell model experiments and revealed rapid uptake of the drug into the cytosol and the nucleus, supporting the hypothesis of passive diffusion as an uptake mechanism.