W
Walter Berger
Researcher at Medical University of Vienna
Publications - 396
Citations - 16667
Walter Berger is an academic researcher from Medical University of Vienna. The author has contributed to research in topics: Cancer & Cell culture. The author has an hindex of 63, co-authored 359 publications receiving 14045 citations. Previous affiliations of Walter Berger include University of Vienna & Université libre de Bruxelles.
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Journal ArticleDOI
Multi-scale imaging of anticancer platinum(iv) compounds in murine tumor and kidney.
Anton A. Legin,Sarah Theiner,Arno Schintlmeister,Siegfried Reipert,Petra Heffeter,Michael A. Jakupec,Josef Mayr,Hristo P. Varbanov,Christian R. Kowol,M. Galanski,Walter Berger,Michael Wagner,Bernhard K. Keppler +12 more
TL;DR: A NanoSIMS, LA-ICP-MS and TEM combinatorial approach was applied to analyze the distribution of platinum(iv) prodrugs in murine tissue samples.
Journal ArticleDOI
Behavior of platinum(iv) complexes in models of tumor hypoxia: cytotoxicity, compound distribution and accumulation.
Ekaterina Schreiber-Brynzak,Verena Pichler,Petra Heffeter,Petra Heffeter,Buck Hanson,Sarah Theiner,Irene Lichtscheidl-Schultz,Christoph Kornauth,Luca Bamonti,Vineet Dhery,Vineet Dhery,Diana Groza,Diana Groza,David Berry,Walter Berger,Walter Berger,Markus Galanski,Michael A. Jakupec,Bernhard K. Keppler +18 more
TL;DR: In this article, a two-step screening of experimental platinum(iv) prodrugs with different rates of reduction and lipophilicity with the aim of identifying the most appropriate compounds for further investigations was conducted.
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The metastatic microenvironment: Claudin-1 suppresses the malignant phenotype of melanoma brain metastasis
Sivan Izraely,Orit Sagi-Assif,Anat Klein,Tsipi Meshel,Shlomit Ben-Menachem,Assaf Zaritsky,Marcelo Ehrlich,Victor G. Prieto,Menashe Bar-Eli,Christine Pirker,Walter Berger,Clara Nahmias,Clara Nahmias,Clara Nahmias,Pierre-Olivier Couraud,Pierre-Olivier Couraud,Pierre-Olivier Couraud,Dave S.B. Hoon,Isaac P. Witz +18 more
TL;DR: It is demonstrated that downregulation or loss of CL DN1 supports the formation of melanoma brain metastasis, and that CLDN1 expression could be a useful prognostic predictor for melanoma patients with a high risk of brain metastases.
Journal ArticleDOI
Fibroblast growth factor receptor 4: a putative key driver for the aggressive phenotype of hepatocellular carcinoma
Christine Gauglhofer,Jakob Paur,Waltraud C. Schrottmaier,Bettina Wingelhofer,Daniela Huber,Isabelle Naegelen,Christine Pirker,Thomas Mohr,Christine Heinzle,Klaus Holzmann,Brigitte Marian,Rolf Schulte-Hermann,Walter Berger,Georg Krupitza,Michael Grusch,Bettina Grasl-Kraupp +15 more
TL;DR: Blockade of FGFR4-mediated signalling by soluble dominant-negative constructs, like solFGFR4, may be a feasible and promising therapeutic approach to antagonize aggressive behaviour of hepatoma/hepatocarcinoma cells.
Journal ArticleDOI
Subcellular Duplex DNA and G‐Quadruplex Interaction Profiling of a Hexagonal PtII Metallacycle
Olaya Domarco,Claudia Kieler,Christine Pirker,Carina Dinhof,Bernhard Englinger,Johannes M. Reisecker,Gerald Timelthaler,Marcos Garcia,Carlos Peinador,Bernhard K. Keppler,Walter Berger,Alessio Terenzi,Alessio Terenzi +12 more
TL;DR: It is shown that the hexagonal supramolecule accumulates in cancer cell nuclei, exerting a distinctive blue fluorescence staining of chromatin resistant to UV photobleaching selectively in nucleolar G4‐rich regions.