W
Wolf H. Fridman
Researcher at University of Paris
Publications - 551
Citations - 60835
Wolf H. Fridman is an academic researcher from University of Paris. The author has contributed to research in topics: Immune system & Receptor. The author has an hindex of 97, co-authored 525 publications receiving 48713 citations. Previous affiliations of Wolf H. Fridman include Queen Elizabeth Hospital Birmingham & Pasteur Institute.
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Procédés de quantification de la population de cellules dendritiques myéloïdes dans un prélèvement de tissu
TL;DR: In this paper, the presente invention concerne des procedes de quantification de la population de cellules T dans un prelevement de tissu, aupres d'un sujet comprenant the determination du niveau d'expression d'au moins un gene selectionne dans le groupe constitue de TRAT1, CD3D, THEMIS, ICOS, SIRPG, CD 3G, CTLA4, CD6, CD5 et CD28.
Journal ArticleDOI
Abstract 3273: Guadecitabine plus ipilimumab in unresectable melanoma: Five-year follow-up and correlation with integrated, multi-omic analysis in the NIBIT-M4 trial
Teresa Maria Rosaria Noviello,Anna Maria Di Giacomo,Francesca Pia Caruso,Alessia Covre,Giovanni Scala,Luigi Ferraro,Sandra Coral,Wolf H. Fridman,Catherine Sautès-Fridman,Roberta Mortarini,Elena Simonetti,Maria Fortunata Lofiego,Davide Bedognetti,Andrea Anichini,M. Ceccarelli,Michele Maio +15 more
TL;DR: The NIBIT-M4 trial as mentioned in this paper reported the 5-year clinical outcome of melanoma patients and its correlation with an integrated multi-omic analysis, including RNA-seq, whole exome sequencing (WES), RRBS methylation profiling, and tumor immune contexture data.
Journal ArticleDOI
Abstract 1342: Roles of mesenchymal-like tumour cells and myofibroblastic cancer-associated fibroblasts in progression and therapeutic response of clear-cell renal cell carcinoma
Alexandra Helleux,Guillaume Davidson,Yann Vano,Véronique Lindner,Antonin Fattori,Marie Cerciat,Reza Elaidi,Virginie Verkarre,Cheng-Ming Sun,Christine Chevreau,Mostefa Bennamoun,Hervé Lang,T. Tricard,Wolf H. Fridman,Catherine Sautès-Fridman,Xiaoping Su,Damien Plassard,Céline Keime,Christelle Thibault-Carpentier,P. Barthelemy,Stéphane Oudard,Irwin Davidson,Gabriel G. Malouf +22 more
TL;DR: Helleux et al. as mentioned in this paper identified 46 cell populations including 5 tumour subpopulations characterized by distinct transcriptional signatures representing an epithelial to mesenchymal transition gradient as well as novel inflamed state.
Journal ArticleDOI
Abstract PR002: Antigen presentation and processing pathway is associated with early relapse after neoadjuvant immune checkpoint blockade (ICB) in dedifferentiated liposarcomas (DDLPS)
Elise F Nassif,Chia Chin Wu,Kadir C. Akdemir,Russell Witt,Raymond Traweek,B. Cope,Prapassorn Thirasastr,Taylor Tate,Grace Mathew,Shadarra Crosby,Randy A. Chu,Mohammad Yasin Mohammad,Kenna R. Shaw,Ingram Davis,Khalida Wani,Alexander J. Lazar,Wei-Lien Wang,Sheila Duncan,Ashleigh Guadagnolo,Andrew J. Bishop,Valerae O. Lewis,Justin E. Bird,Keila E. Torres,Kelly K. Hunt,Barry W. Feig,Christopher P. Scally,Ravin Ratan,Shreyaskumar Patel,Robert S. Benjamin,Robert L. Satcher,Kevin M. McBride,Wolf H. Fridman,Ignacio I. Wistuba,P. Andrew Futreal,Jennifer A. Wargo,Neeta Somaiah,Christina L. Roland,Emily Z. Keung +37 more
TL;DR: Antigen presentation and processing is a major driver of response to immunotherapy and future efforts should focus on identifying which antigens are presented to find synergizing compounds in order to increase the clinical benefit of neoadjuvant ICB.