Wolf H. Fridman

TL;DR: The possibility that Fc gamma RII expressing tumor cells could interfere with the immune system was tested and it was found that aggregated mouse IgG (as well as IgGl) could stimulate the proliferation of the T cell hybridoma (T2D4) and other Fc Gamma R II expressing T cells.

TL;DR: Sturm et al. as mentioned in this paper developed a systematic approach for benchmarking such computational methods and assessed the accuracy of tools at estimating nine different immune- and stromal cells from bulk RNA-seq samples.

TL;DR: It is shown, by using two cell lines representative of B and mast cells, that different promoter fragments determine, in these two cell types, the transcription of the β FcγR gene.

TL;DR: PBL from NPC patients exhibited a normal proliferative response to phytohemagglutinin and Concanavalin A (Con A) and an increased response to pokeweed mitogen (PWM), and a lack of cytotoxicity against an EBV‐transformed B‐cell line cannot be explained by an impairment of IL‐2 secretion, and is probably a result of the presence of high numbers of OKT8 suppressor T cells.

TL;DR: A low sCD16 level in MGUS indicated a high likelihood of rapid evolution to multiple myeloma, and soluble IL‐6R did not appear to be discriminant in this study.