Wolf H. Fridman

TL;DR: It is demonstrated that the brain is able to recruit all the major actors to mount a specific anti‐tumour immune response against lymphoma, and that nude mice that received lymphoma cells intracerebrally died significantly earlier than immunocompetent animals.

TL;DR: In this paper, a method for the production and selection of human or chimaeric or humanized antibodies or molecules that comprise the Fc region of human IgG, capable of modulating the activity of one or several particular Fc receptors, such as the triggering of inhibitory functions through the human type IIB receptors of IgG (FcgammaRIIB/CD32).

TL;DR: The dosage of FcRs and IBFs could bring new insights in the monitoring of B cell proliferations, including B-CLL, and the significance of these data has to be envisioned in view of the possible role of immunoglobulin-Binding Factors (IBF), FcR-related immunoregulatory lymphokines, in the control of B Cell proliferation.

TL;DR: The kinetics of action of T-interferon on antibody synthesis show that it interferes with the early events of lymphocyte activation, and when titrated on the basis of antiviral activity no quantitative difference in the inhibition of antibody synthesis could be found.

TL;DR: The transfection, production and purification techniques which allow the preparation of milligram amounts of glycosylated recombinant mouse and human soluble Fcγ receptors, which bind IgG and are biologically active on immune responses, like their normal counterparts are described.