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Wolf H. Fridman
Researcher at University of Paris
Publications - 551
Citations - 60835
Wolf H. Fridman is an academic researcher from University of Paris. The author has contributed to research in topics: Immune system & Receptor. The author has an hindex of 97, co-authored 525 publications receiving 48713 citations. Previous affiliations of Wolf H. Fridman include Queen Elizabeth Hospital Birmingham & Pasteur Institute.
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Human cytotoxic T lymphocytes (CTL) against Epstein-Barr virus (EBV) infected cells: EBV specificity and involvement of major histocompatibility complex determinants in the lysis exerted by anti-EBV CTL toward HLA-compatible and allogeneic target cells.
TL;DR: The data suggest that human anti-EBV CTL may recognize nonpolymorphic HLA determinants on the target cells in association with the virus-induced antigens.
Journal Article
[CD4 TIL (Tumor Infiltrating Lymphocytes) induce complete response in patients treated with IL-2 (Interleukin-2). Preliminary study].
Nicolas Thiounn,Claire Mathiot,Thierry Flam,Eric Tartour,Peyret C,Isabelle Joyeux,Abecassis Jp,Marc Zerbib,Wolf H. Fridman,Bernard Debré +9 more
TL;DR: CD4 TIL may improve an initially response induced by IL-2 therapy, and is shown to lead to an amelioration for 4 patients with renal cell carcinoma previously treated by interleukin-2.
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NIVOREN GETUG-AFU 26 translational study: Association of PD-1, AXL, and PBRM-1 with outcomes in patients (pts) with metastatic clear cell renal cell carcinoma (mccRCC) treated with nivolumab (N).
Yann-Alexandre Vano,Nathalie Rioux-Leclercq,Cécile Dalban,Catherine Sautès-Fridman,Antoine Bougoüin,Nathalie Chaput,Salem Chouaib,Benoit Beuselinck,Christine Chevreau,Marine Gross-Goupil,Sylvie Negrier,Brigitte Laguerre,Delphine Borchiellini,Irelka Colina-Moreno,Wolf H. Fridman,Sylvie Chabaud,Florence Tantot,Janice Barros Monteiro,Bernard Escudier,Laurence Albiges +19 more
TL;DR: The NIVOREN GETUG-AFU 26 study reported safety and efficacy of N in mccRCC pts in a “real world setting” and launched a translationnal research program to characterize immune cell p...
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Effect of zinc on human IgG1 and its FcγR interactions
Sophie Sibéril,Renée Ménez,Sylvie Jorieux,Christophe De Romeuf,Dominique Bourel,Wolf H. Fridman,Wolf H. Fridman,Wolf H. Fridman,Frédéric Ducancel,Enrico A. Stura,Jean-Luc Teillaud,Jean-Luc Teillaud,Jean-Luc Teillaud +12 more
TL;DR: It is shown that histidines 310 and 435 at the CH2-CH3 interface of the Fc portion of human IgG1 can coordinate a Zn2+ and participate in the control of the CH3-CH2 interdomain opening, suggesting that zinc could be an important control factor in IgG 1/FcγR interactions.