W
Wolf H. Fridman
Researcher at University of Paris
Publications - 551
Citations - 60835
Wolf H. Fridman is an academic researcher from University of Paris. The author has contributed to research in topics: Immune system & Receptor. The author has an hindex of 97, co-authored 525 publications receiving 48713 citations. Previous affiliations of Wolf H. Fridman include Queen Elizabeth Hospital Birmingham & Pasteur Institute.
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Journal Article
Structure of the mouse beta Fc gamma receptor II gene.
P. M. Hogarth,Ewa Witort,Mark D. Hulett,C. Bonnerot,Even J,Wolf H. Fridman,Ian F. C. McKenzie +6 more
TL;DR: Analysis of the gene structure indicated that the beta 1Fc Gamma RII and beta 2Fc gamma RII arise by differential mRNA splicing when a single 141-bp exon is alternately spliced to give rise to these isoforms.
Journal ArticleDOI
Comparison of effects of leukocyte and fibroblast interferon on immunological parameters in cancer patients.
Miguel A. Lucero,Henri Magdelenat,Wolf H. Fridman,Pierre Pouillart,Claude Billardon,Alfons Billiau,K. Cantell,Ernesto Falcoff +7 more
TL;DR: Patients with metastatic cancer were given single intramuscular injections of 10(7) units of partially purified preparations of either leukocyte or fibroblast IFN and the natural killer activity of circulating lymphocytes was enhanced with both IFNs.
Journal Article
Tyrosine-containing activation motif-dependent phagocytosis in mast cells.
TL;DR: It is demonstrated that tyrosines in the TAM sequence are required for phagocytosis and endow TAM gamma with previously unknown triggering capacities and Fc gamma RIII with new biologic properties.
Journal Article
Characterization of soluble gp130 released by melanoma cell lines: A polyvalent antagonist of cytokines from the interleukin 6 family.
F.A. Montero-Julian,H. Brailly,Catherine Sautes,Isabelle Joyeux,Thierry Dorval,Véronique Mosseri,K Yasukawa,John Wijdenes,A Adler,I Gorin,Wolf H. Fridman,Eric Tartour +11 more
TL;DR: It is demonstrated that melanoma cell lines release, in vitro and in vivo (when transplanted in nude mice), soluble gp130 (sgp130), a potential antagonist of cytokines from the IL-6 family.
Journal ArticleDOI
Quantitative Analyses of the Tumor Microenvironment Composition and Orientation in the Era of Precision Medicine.
Florent Petitprez,Cheng-Ming Sun,Cheng-Ming Sun,Cheng-Ming Sun,Laetitia Lacroix,Laetitia Lacroix,Laetitia Lacroix,Catherine Sautès-Fridman,Catherine Sautès-Fridman,Catherine Sautès-Fridman,Aurélien de Reyniès,Wolf H. Fridman,Wolf H. Fridman,Wolf H. Fridman +13 more
TL;DR: An overview of experimental and computational methodologies used to quantify tumor-associated cellular populations, including immunohistochemistry, flow and mass cytometry, bulk and single-cell transcriptomic approaches, are provided and their respective contribution to characterize the microenvironment is illustrated.