W
Wonil Chung
Researcher at Harvard University
Publications - 27
Citations - 2800
Wonil Chung is an academic researcher from Harvard University. The author has contributed to research in topics: Genome-wide association study & Asthma. The author has an hindex of 13, co-authored 23 publications receiving 1866 citations. Previous affiliations of Wonil Chung include Soongsil University & Seoul National University.
Papers
More filters
Journal ArticleDOI
Integrative approaches for large-scale transcriptome-wide association studies.
Alexander Gusev,Alexander Gusev,Arthur Ko,Huwenbo Shi,Gaurav Bhatia,Gaurav Bhatia,Wonil Chung,Brenda W.J.H. Penninx,Rick Jansen,Eco J. C. de Geus,Dorret I. Boomsma,Fred A. Wright,Patrick F. Sullivan,Patrick F. Sullivan,Elina Nikkola,Marcus Alvarez,Mete Civelek,Aldons J. Lusis,Terho Lehtimäki,Emma Raitoharju,Mika Kähönen,Ilkka Seppälä,Olli T. Raitakari,Olli T. Raitakari,Johanna Kuusisto,Markku Laakso,Alkes L. Price,Alkes L. Price,Päivi Pajukanta,Bogdan Pasaniuc +29 more
TL;DR: A powerful strategy that integrates gene expression measurements with summary association statistics from large-scale genome-wide association studies (GWAS) to identify genes whose cis-regulated expression is associated with complex traits is introduced.
Journal ArticleDOI
Heritability and genomics of gene expression in peripheral blood
Fred A. Wright,Patrick F. Sullivan,Andrew Brooks,Fei Zou,Wei Sun,Kai Xia,Vered Madar,Rick Jansen,Wonil Chung,Yi-Hui Zhou,Abdel Abdellaoui,Sandra Batista,Casey Butler,Guanhua Chen,Ting Huei Chen,David D'Ambrosio,Paul J. Gallins,Min Jin Ha,Jouke-Jan Hottenga,Shunping Huang,Mathijs Kattenberg,Jaspreet Kochar,Christel M. Middeldorp,Ani Qu,Andrey A. Shabalin,Jay A. Tischfield,Laura Todd,Jung-Ying Tzeng,Gerard van Grootheest,Jacqueline M. Vink,Qi Wang,Wei Wang,Weibo Wang,Gonneke Willemsen,Johannes H. Smit,Eco J. C. de Geus,Zhaoyu Yin,Brenda W.J.H. Penninx,Dorret I. Boomsma +38 more
TL;DR: Gen expression profiles in 2,752 twins were assessed, using a classic twin design, to quantify expression heritability and quantitative trait loci (eQTLs) in peripheral blood, providing a new resource toward understanding the genetic control of transcription.
Journal ArticleDOI
Shared genetic and experimental links between obesity-related traits and asthma subtypes in UK Biobank
Zhaozhong Zhu,Yanjun Guo,Huwenbo Shi,Cong-Lin Liu,Ronald Allan M Panganiban,Wonil Chung,Luke J. O’Connor,Blanca E. Himes,Steven Gazal,Kohei Hasegawa,Carlos A. Camargo,Lu Qi,Miriam F. Moffatt,Frank B. Hu,Quan Lu,William O.C.M. Cookson,Liming Liang +16 more
TL;DR: This work identified shared genetic components between obesity-related traits and specific asthma subtypes, reinforcing the hypothesis that obesity causally increases the risk of asthma, and identifying molecular pathways that may underlie both obesity and asthma.
Journal ArticleDOI
A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.
Zhou Zhu,Phil Lee,Phil Lee,Mark Chaffin,Wonil Chung,Po-Ru Loh,Po-Ru Loh,Qun Lu,David C. Christiani,Liming Liang +9 more
TL;DR: This work identifies common genetic architectures shared between asthma and allergy and will help to advance understanding of the molecular mechanisms underlying co-morbid asthma and allergic diseases.
Journal ArticleDOI
The Mediterranean diet, plasma metabolome, and cardiovascular disease risk.
Jun Li,Marta Guasch-Ferré,Marta Guasch-Ferré,Wonil Chung,Miguel Ruiz-Canela,Miguel Ruiz-Canela,Estefanía Toledo,Estefanía Toledo,Dolores Corella,Dolores Corella,Shilpa N Bhupathiraju,Shilpa N Bhupathiraju,Deirdre K Tobias,Deirdre K Tobias,Fred K. Tabung,Fred K. Tabung,Jie Hu,Tong Zhao,Constance Turman,Yen-Chen Anne Feng,Yen-Chen Anne Feng,Clary B. Clish,Lorelei A. Mucci,A. Heather Eliassen,A. Heather Eliassen,Karen H. Costenbader,Elizabeth W. Karlson,Brian M. Wolpin,Alberto Ascherio,Alberto Ascherio,Eric B. Rimm,Eric B. Rimm,JoAnn E. Manson,JoAnn E. Manson,Lu Qi,Lu Qi,Lu Qi,Miguel Ángel Martínez-González,Jordi Salas-Salvadó,Frank B. Hu,Frank B. Hu,Liming Liang +41 more
TL;DR: A metabolic signature is identified that robustly reflects adherence and metabolic response to a Mediterranean diet, and predicts future CVD risk independent of traditional risk factors, in Spanish and US cohorts.