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Xiang He

Researcher at Centers for Disease Control and Prevention

Publications -  67
Citations -  1641

Xiang He is an academic researcher from Centers for Disease Control and Prevention. The author has contributed to research in topics: Population & Virus. The author has an hindex of 21, co-authored 63 publications receiving 1384 citations. Previous affiliations of Xiang He include Chinese Center for Disease Control and Prevention & Beihang University.

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A comprehensive mapping of HIV-1 genotypes in various risk groups and regions across China based on a nationwide molecular epidemiologic survey.

TL;DR: This study provides the first comprehensive baseline data on the diversity and characteristics of HIV/AIDS epidemic in China, reflecting unique region- and risk group-specific transmission dynamics.
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Global and regional molecular epidemiology of HIV-1, 1990–2015: a systematic review, global survey, and trend analysis

Joris Hemelaar, +181 more
TL;DR: The distribution of HIV-1 subtypes and recombinants changed over time in countries, regions, and globally as well as at a global level during 2005-15, where subtype B increased, subtypes A and D were stable, and subtypes C and G and CRF02_AG decreased.
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The rapidly expanding CRF01_AE epidemic in China is driven by multiple lineages of HIV-1 viruses introduced in the 1990s.

TL;DR: In this paper, the authors comprehensively analyzed the origin, transmission patterns and sub-epidemic clusters of the HIV-1 CRF01_AE strains in China and found that the transmission patterns of these strains are similar to those of the AIDS strain.
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Tracing the origin and history of HIV-1 subtype B' epidemic by near full-length genome analyses.

TL;DR: It is suggested that Yunnan province plays a pivotal role in bridging the preexisting subtype B′ epidemics in south-east Asia with the subsequent epidemic among FPDs and heterosexuals in inland China.
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Geographic origin and evolutionary history of China's two predominant HIV-1 circulating recombinant forms, CRF07_BC and CRF08_BC

TL;DR: The results provide compelling evidence for western Yunnan as the geographic origin of CRF07_BC and CRF08_BC, which emerged from a swarm of URFs_BC by a series of recombination events in western Yun Nan in the early 1990s.