C
Cillian De Gascun
Researcher at University College Dublin
Publications - 69
Citations - 1584
Cillian De Gascun is an academic researcher from University College Dublin. The author has contributed to research in topics: Medicine & Population. The author has an hindex of 16, co-authored 58 publications receiving 1067 citations. Previous affiliations of Cillian De Gascun include Beaumont Hospital & Frimley Park Hospital.
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Journal ArticleDOI
Geographic and temporal trends in the molecular epidemiology and genetic mechanisms of transmitted HIV-1 drug resistance: an individual-patient- and sequence-level meta-analysis
Soo-Yon Rhee,José Luis Santiago Blanco,Michael R. Jordan,Jonathan Taylor,Philippe Lemey,Vici Varghese,Raph L. Hamers,Silvia Bertagnolio,Tobias F. Rinke de Wit,Avelin F. Aghokeng,Jan Albert,Radko Avi,Santiago Ávila-Ríos,Pascal O. Bessong,James Brooks,Charles A. Boucher,Zabrina L. Brumme,Michael P. Busch,Hermann Bussmann,Marie Laure Chaix,Bum Sik Chin,Toni T. D’Aquin,Cillian De Gascun,Anne Derache,Diane Descamps,Alaka Deshpande,Cyrille F. Djoko,Susan H. Eshleman,Hervé Fleury,Pierre Frange,Seiichiro Fujisaki,P. Richard Harrigan,Junko Hattori,África Holguín,Gillian Hunt,Hiroshi Ichimura,Pontiano Kaleebu,David Katzenstein,Sasisopin Kiertiburanakul,Jerome H. Kim,Sung Soon Kim,Yanpeng Li,Irja Lutsar,Lynn Morris,Nicaise Ndembi,Kee Peng Ng,Ramesh S. Paranjape,Martine Peeters,Mario Poljak,Matthew Price,Manon Ragonnet-Cronin,Gustavo Reyes-Terán,Morgane Rolland,Sunee Sirivichayakul,Davey M. Smith,Marcelo A. Soares,Vincent Soriano,Deogratius Ssemwanga,Maja Stanojevic,Mariane A. Stefani,Wataru Sugiura,Somnuek Sungkanuparph,Amilcar Tanuri,Kok Keng Tee,Hong-Ha M. Truong,David A. M. C. van de Vijver,Nicole Vidal,Chunfu Yang,Rongge Yang,Gonzalo Yebra,John P. A. Ioannidis,Anne-Mieke Vandamme,Robert W. Shafer +72 more
TL;DR: Most TDR strains in SSA and SSEA arose independently, suggesting that ARV regimens with a high genetic barrier to resistance combined with improved patient adherence may mitigate TDR increases by reducing the generation of new ARV-resistant strains.
Journal ArticleDOI
Global and regional molecular epidemiology of HIV-1, 1990–2015: a systematic review, global survey, and trend analysis
Joris Hemelaar,Ramyiadarsini Elangovan,Jason Yun,Leslie Dickson-Tetteh,Isabella Fleminger,Shona Kirtley,Brian G. Williams,Eleanor Gouws-Williams,Peter D. Ghys,Alash'le Abimiku,Simon Agwale,Chris P. Archibald,Boaz Avidor,María Gabriela Barbás,Françoise Barré-Sinoussi,Banson Barugahare,El Hadj Belabbes,Silvia Bertagnolio,Deborah L. Birx,Aleksei F Bobkov,James Brandful,Helba Bredell,Catherine A. Brennan,James Brooks,Marie Bruckova,Luigi Buonaguro,Franco M. Buonaguro,Stefano Buttò,Anne Buvé,Mary S. Campbell,Jean K. Carr,Alex Carrera,Manuel Gómez Carrillo,Connie Celum,Beth Chaplin,Macarthur Charles,Dimitrios Chatzidimitriou,Zhiwei Chen,Katsumi Chijiwa,David Cooper,Philip Cunningham,Anoumou Y. Dagnra,Cillian De Gascun,Julia del Amo,Elena Delgado,Ursula Dietrich,Dominic M. Dwyer,Dennis Ellenberger,Barbara Ensoli,Max Essex,Feng Gao,Hervé Fleury,Peter N. Fonjungo,Vincent Foulongne,Deepak A Gadkari,Federico García,Roger Garsia,Guy Michel Gershy-Damet,Judith R. Glynn,Ruth Goodall,Zehava Grossman,Monick Lindenmeyer-Guimarães,Beatrice H. Hahn,Raph L. Hamers,Osamah Hamouda,Ray Handema,Xiang He,Joshua T. Herbeck,David D. Ho,África Holguín,Mina C. Hosseinipour,Gillian Hunt,Masahiko Ito,Mohamed Ali Bel Hadj Kacem,Erin M. Kahle,Pontiano Kaleebu,Marcia L. Kalish,Adeeba Kamarulzaman,Chun Kang,Phyllis J. Kanki,Edward Karamov,Jean-Claude Karasi,Kayitesi Kayitenkore,Tony Kelleher,Dwip Kitayaporn,Leondios G. Kostrikis,Claudia Kücherer,Claudia Lara,Thomas Leitner,Kirsi Liitsola,J.R. Lingappa,Marek Linka,Ivette Lorenzana de Rivera,Vladimir Lukashov,Shlomo Maayan,Luzia Mayr,Francine E. McCutchan,Nicolas Meda,Elisabeth Menu,Fred Mhalu,Doreen Mloka,John L. Mokili,Brigitte Montes,Orna Mor,Mariza G. Morgado,Fausta Mosha,Awatef Moussi,James I. Mullins,Rafael Nájera,Mejda Nasr,Nicaise Ndembi,Joel R. Neilson,Vivek R. Nerurkar,Florian Neuhann,Claudine Nolte,Vlad Novitsky,Philippe Nyambi,Marianna Ofner,Fem J Paladin,Anna Papa,Jean Pape,Neil Parkin,Christopher M. Parry,Martine Peeters,Alexandra Pelletier,Lucía Pérez-Álvarez,Deenan Pillay,Angie N Pinto,Trinh Duy Quang,Cecilia Rademeyer,Filimone Raikanikoda,Mark A. Rayfield,Jean-Marc Reynes,Tobias F. Rinke de Wit,Kenneth E. Robbins,Morgane Rolland,Christine Rousseau,Jesus Salazar-Gonzales,Hanan Salem,Mika Salminen,Horacio Salomon,Paul Sandstrom,Mario L. Santiago,Abdoulaye Dieng Sarr,Bryan Schroeder,Michel Segondy,Philippe Selhorst,Sylvester Sempala,Jean Servais,Ansari Shaik,Yiming Shao,Amine Slim,Marcelo A. Soares,Elijah M. Songok,Debbie Stewart,Julie Stokes,Shambavi Subbarao,Ruengpung Sutthent,Jun Takehisa,Amilcar Tanuri,Kok Keng Tee,Kiran Thapa,Michael M. Thomson,Tyna Tran,Willy Urassa,Hiroshi Ushijima,Philippe Van de Perre,Guido van der Groen,Kristel Van Laethem,Joep J. van Oosterhout,Ard van Sighem,Eric Van Wijngaerden,Anne-Mieke Vandamme,Jurgen Vercauteren,Nicole Vidal,Lesley Wallace,Carolyn Williamson,Dawit Wolday,Jianqing Xu,Chunfu Yang,Linqi Zhang,Rong Zhang +181 more
TL;DR: The distribution of HIV-1 subtypes and recombinants changed over time in countries, regions, and globally as well as at a global level during 2005-15, where subtype B increased, subtypes A and D were stable, and subtypes C and G and CRF02_AG decreased.
Journal ArticleDOI
HIV-1 subtype distribution and its demographic determinants in newly diagnosed patients in Europe suggest highly compartmentalized epidemics
Ana B. Abecasis,Annemarie M. J. Wensing,D Paraskevis,Jurgen Vercauteren,Jurgen Vercauteren,Kristof Theys,David A. M. C. van de Vijver,Jan Albert,Jan Albert,Birgitta Åsjö,Claudia Balotta,Danail Beshkov,Ricardo Jorge Camacho,Bonaventura Clotet,Cillian De Gascun,Algis Griskevicius,Zehava Grossman,Osamah Hamouda,Andrzej Horban,Tatjana Kolupajeva,Klaus Korn,Leon G. Kostrikis,Claudia Kücherer,Kirsi Liitsola,Marek Linka,Claus Nielsen,Dan Otelea,Roger Paredes,Mario Poljak,Elisabeth Puchhammer-Stöckl,Jean-Claude Schmit,Anders Sönnerborg,Danika Stanekova,Maja Stanojevic,Daniel Struck,Charles A. Boucher,Anne-Mieke Vandamme,Anne-Mieke Vandamme +37 more
TL;DR: The association of subtype with demographic parameters suggests highly compartmentalized epidemics, determined by social and behavioural characteristics of the patients, suggests they acquired their infection there or in Europe from compatriots.
Journal ArticleDOI
The duration of infectiousness of individuals infected with SARS-CoV-2.
Kieran A. Walsh,Susan Spillane,Laura Comber,Karen Cardwell,P. Harrington,Jeff Connell,Conor Teljeur,Natasha Broderick,Cillian De Gascun,Susan M Smith,Máirín Ryan,Michelle O'Neill +11 more
TL;DR: Evidence from a limited number of studies indicates that patients with severe-to-critical illness or who are immunocompromised, may shed infectious virus for longer, but patients with mild- to-moderate illness are highly unlikely to be infectious beyond 10 days of symptoms.
Journal ArticleDOI
Human Polyomavirus Reactivation: Disease Pathogenesis and Treatment Approaches
TL;DR: This review summarises the human polyomaviruses with particular emphasis on pathogenesis in those directly implicated in disease aetiology and the therapeutic options available for treatment in the immunocompromised host.