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Xiaotong Wang
Researcher at Chinese Academy of Sciences
Publications - 24
Citations - 2065
Xiaotong Wang is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 7, co-authored 10 publications receiving 1750 citations.
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Journal ArticleDOI
The oyster genome reveals stress adaptation and complexity of shell formation
Guofan Zhang,Xiaodong Fang,Ximing Guo,Li Li,Ruibang Luo,Fei Xu,Pengcheng Yang,Linlin Zhang,Xiaotong Wang,Haigang Qi,Zhiqiang Xiong,Huayong Que,Yinlong Xie,Peter W. H. Holland,Jordi Paps,Yabing Zhu,Fucun Wu,Yuanxin Chen,Jiafeng Wang,Chunfang Peng,Jie Meng,Lan Yang,Jun Liu,Bo Wen,Na Zhang,Zhiyong Huang,Qihui Zhu,Yue Feng,Andrew S. Mount,Dennis Hedgecock,Zhe Xu,Yunjie Liu,Tomislav Domazet-Lošo,Yishuai Du,Xiaoqing Sun,Shoudu Zhang,Binghang Liu,Peizhou Cheng,Xuanting Jiang,Juan Li,Dingding Fan,Wei Wang,Wenjing Fu,Tong Wang,Bo Wang,Jibiao Zhang,Zhiyu Peng,Yingxiang Li,Na Li,Jinpeng Wang,Maoshan Chen,Yan He,Fengji Tan,Xiaorui Song,Qiumei Zheng,Ronglian Huang,Hailong Yang,Du Xuedi,Li Chen,Mei Yang,Patrick M. Gaffney,Shan Wang,Longhai Luo,Zhicai She,Yao Ming,Huang Wen,Shu Zhang,Baoyu Huang,Yong Zhang,Tao Qu,Peixiang Ni,Guoying Miao,Junyi Wang,Qiang Wang,Christian E. W. Steinberg,Haiyan Wang,Ning Li,Lumin Qian,Guojie Zhang,Yingrui Li,Huanming Yang,Xiao Liu,Jian Wang,Ye Yin,Jun Wang +84 more
TL;DR: The sequencing and assembly of the oyster genome using short reads and a fosmid-pooling strategy and transcriptomes of development and stress response and the proteome of the shell are reported, showing that shell formation in molluscs is more complex than currently understood and involves extensive participation of cells and their exosomes.
Journal ArticleDOI
Genome-wide and single-base resolution DNA methylomes of the Pacific oyster Crassostrea gigas provide insight into the evolution of invertebrate CpG methylation
Xiaotong Wang,Qiye Li,Jinmin Lian,Li Li,Lijun Jin,Huimin Cai,Fei Xu,Haigang Qi,Linlin Zhang,Fucun Wu,Jie Meng,Huayong Que,Xiaodong Fang,Ximing Guo,Guofan Zhang +14 more
TL;DR: Comparative analysis of the oyster DNA methylomes and that of other animal species revealed that the characteristics of DNA methylation were generally conserved during invertebrate evolution, while some unique features were derived in the insect lineage.
Journal ArticleDOI
Oyster Shell Proteins Originate from Multiple Organs and Their Probable Transport Pathway to the Shell Formation Front
Xiaotong Wang,Li Li,Yabing Zhu,Yishuai Du,Xiaorui Song,Yuanxin Chen,Ronglian Huang,Huayong Que,Xiaodong Fang,Guofan Zhang +9 more
TL;DR: It is found that the shell proteins may be produced by multiple organs though the mantle is still the most important organ for shell formation, and a new immature model is proposed, which will help to think about the mechanism of shell formation in a different way.
Journal ArticleDOI
Identification of Conserved and Novel MicroRNAs in the Pacific Oyster Crassostrea gigas by Deep Sequencing
Fei Xu,Xiaotong Wang,Yue Feng,Huang Wen,Wei Wang,Li Li,Xiaodong Fang,Huayong Que,Guofan Zhang +8 more
TL;DR: Deep sequencing was conducted to identify the miRNAs of Crassostrea gigas (Lophotrochozoa) at a genomic scale, using 21 libraries that included different developmental stages and adult organs, and it was found that the swimming stages were characterized by the youngest miRPAIs.
Journal ArticleDOI
Identification two novel nacrein-like proteins involved in the shell formation of the Pacific oyster Crassostrea gigas
TL;DR: Surprisingly, the Gly-X-Asn repeat domain was absent in the two newly identified nacrein-like proteins in C. gigas and replaced with a series of acidic amino acids (D/E).