Z
Zhiyong Huang
Researcher at Beijing Genomics Institute
Publications - 28
Citations - 8584
Zhiyong Huang is an academic researcher from Beijing Genomics Institute. The author has contributed to research in topics: Genome & Comparative genomics. The author has an hindex of 23, co-authored 28 publications receiving 7455 citations.
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Journal ArticleDOI
The oyster genome reveals stress adaptation and complexity of shell formation
Guofan Zhang,Xiaodong Fang,Ximing Guo,Li Li,Ruibang Luo,Fei Xu,Pengcheng Yang,Linlin Zhang,Xiaotong Wang,Haigang Qi,Zhiqiang Xiong,Huayong Que,Yinlong Xie,Peter W. H. Holland,Jordi Paps,Yabing Zhu,Fucun Wu,Yuanxin Chen,Jiafeng Wang,Chunfang Peng,Jie Meng,Lan Yang,Jun Liu,Bo Wen,Na Zhang,Zhiyong Huang,Qihui Zhu,Yue Feng,Andrew S. Mount,Dennis Hedgecock,Zhe Xu,Yunjie Liu,Tomislav Domazet-Lošo,Yishuai Du,Xiaoqing Sun,Shoudu Zhang,Binghang Liu,Peizhou Cheng,Xuanting Jiang,Juan Li,Dingding Fan,Wei Wang,Wenjing Fu,Tong Wang,Bo Wang,Jibiao Zhang,Zhiyu Peng,Yingxiang Li,Na Li,Jinpeng Wang,Maoshan Chen,Yan He,Fengji Tan,Xiaorui Song,Qiumei Zheng,Ronglian Huang,Hailong Yang,Du Xuedi,Li Chen,Mei Yang,Patrick M. Gaffney,Shan Wang,Longhai Luo,Zhicai She,Yao Ming,Huang Wen,Shu Zhang,Baoyu Huang,Yong Zhang,Tao Qu,Peixiang Ni,Guoying Miao,Junyi Wang,Qiang Wang,Christian E. W. Steinberg,Haiyan Wang,Ning Li,Lumin Qian,Guojie Zhang,Yingrui Li,Huanming Yang,Xiao Liu,Jian Wang,Ye Yin,Jun Wang +84 more
TL;DR: The sequencing and assembly of the oyster genome using short reads and a fosmid-pooling strategy and transcriptomes of development and stress response and the proteome of the shell are reported, showing that shell formation in molluscs is more complex than currently understood and involves extensive participation of cells and their exosomes.
Journal ArticleDOI
Comparative genomics reveals insights into avian genome evolution and adaptation.
Guojie Zhang,Guojie Zhang,Cai Li,Qiye Li,Bo Li,Denis M. Larkin,Chul Hee Lee,Jay F. Storz,Agostinho Antunes,Matthew J. Greenwold,Robert W. Meredith,Anders Ödeen,Jie Cui,Qi Zhou,Luohao Xu,Hailin Pan,Zongji Wang,Lijun Jin,Pei Zhang,Haofu Hu,Wei Yang,Jiang Hu,Jin Xiao,Zhikai Yang,Yang Liu,Qiaolin Xie,Hao Yu,Jinmin Lian,Ping Wen,Fang Zhang,Hui Li,Yongli Zeng,Zijun Xiong,Shiping Liu,Long Zhou,Zhiyong Huang,Na An,Jie Wang,Qiumei Zheng,Yingqi Xiong,Guangbiao Wang,Bo Wang,Jingjing Wang,Yu Fan,Rute R. da Fonseca,Alonzo Alfaro-Núñez,Mikkel Schubert,Ludovic Orlando,Tobias Mourier,Jason T. Howard,Ganeshkumar Ganapathy,Andreas R. Pfenning,Osceola Whitney,Miriam V. Rivas,Erina Hara,Julia Smith,Marta Farré,Jitendra Narayan,Gancho T. Slavov,Michael N Romanov,Rui Borges,João Paulo Machado,Imran Khan,Mark S. Springer,John Gatesy,Federico G. Hoffmann,Juan C. Opazo,Olle Håstad,Roger H. Sawyer,Heebal Kim,Kyu-Won Kim,Hyeon Jeong Kim,Seoae Cho,Ning Li,Yinhua Huang,Michael William Bruford,Xiangjiang Zhan,Andrew Dixon,Mads F. Bertelsen,Elizabeth P. Derryberry,Wesley C. Warren,Richard K. Wilson,Shengbin Li,David A. Ray,Richard E. Green,Stephen J. O'Brien,Darren K. Griffin,Warren E. Johnson,David Haussler,Oliver A. Ryder,Eske Willerslev,Gary R. Graves,Per Alström,Jon Fjeldså,David P. Mindell,Scott V. Edwards,Edward L. Braun,Carsten Rahbek,David W. Burt,Peter Houde,Yong Zhang,Huanming Yang,Jian Wang,Erich D. Jarvis,M. Thomas P. Gilbert,M. Thomas P. Gilbert,Jun Wang +106 more
TL;DR: This work explored bird macroevolution using full genomes from 48 avian species representing all major extant clades to reveal that pan-avian genomic diversity covaries with adaptations to different lifestyles and convergent evolution of traits.
Journal ArticleDOI
The yak genome and adaptation to life at high altitude
Qiang Qiu,Guojie Zhang,Tao Ma,Wubin Qian,Junyi Wang,Zhiqiang Ye,Chang-Chang Cao,Quanjun Hu,Jaebum Kim,Jaebum Kim,Denis M. Larkin,Loretta Auvil,Boris Capitanu,Jian Ma,Harris A. Lewin,Xiaoju Qian,Yongshan Lang,Ran Zhou,Lizhong Wang,Kun Wang,Jinquan Xia,Shengguang Liao,Shengkai Pan,Xu Lu,Haolong Hou,Yan Wang,Xuetao Zang,Ye Yin,Hui Ma,Jian Zhang,Zhaofeng Wang,Yingmei Zhang,Dawei Zhang,Takahiro Yonezawa,Masami Hasegawa,Yang Zhong,Wenbin Liu,Yan Zhang,Zhiyong Huang,Shengxiang Zhang,Ruijun Long,Huanming Yang,Jian Wang,Johannes A. Lenstra,David Neil Cooper,Yi Wu,Jun Wang,Jun Wang,Peng Shi,Jianquan Liu,Jianquan Liu +50 more
TL;DR: Positively selected and rapidly evolving genes in the yak lineage are found to be significantly enriched in functional categories and pathways related to hypoxia and nutrition metabolism, which may have important implications for understanding adaptation to high altitude in other animal species and for Hypoxia-related diseases in humans.
Journal ArticleDOI
Genome sequencing reveals insights into physiology and longevity of the naked mole rat
Eun Bae Kim,Xiaodong Fang,Alexey A. Fushan,Zhiyong Huang,Alexei Lobanov,Lijuan Han,Stefano M. Marino,Xiaoqing Sun,Anton A. Turanov,Pengcheng Yang,Sun Hee Yim,Xiang Zhao,Marina V. Kasaikina,Nina Stoletzki,Chunfang Peng,Paz Polak,Zhiqiang Xiong,Adam Kiezun,Yabing Zhu,Yuanxin Chen,Gregory V. Kryukov,Qiang Zhang,Leonid Peshkin,Lan Yang,Roderick T. Bronson,Rochelle Buffenstein,Bo Wang,Changlei Han,Qiye Li,Li Chen,Wei Zhao,Shamil R. Sunyaev,Thomas J. Park,Guojie Zhang,Jun Wang,Vadim N. Gladyshev +35 more
TL;DR: The sequencing and analysis of the naked mole rat genome is reported, which reveals unique genome features and molecular adaptations consistent with cancer resistance, poikilothermy, hairlessness and insensitivity to low oxygen, and altered visual function, circadian rythms and taste sensing.
Journal ArticleDOI
Corrigendum: Genome-wide adaptive complexes to underground stresses in blind mole rats Spalax.
Xiaodong Fang,Eviatar Nevo,Lijuan Han,Erez Y. Levanon,Jing Zhao,Aaron Avivi,Denis M. Larkin,Xuanting Jiang,Sergey Feranchuk,Yabing Zhu,Alla Fishman,Yue Feng,Noa Sher,Zhiqiang Xiong,Thomas Hankeln,Zhiyong Huang,Vera Gorbunova,Lu Zhang,Wei Zhao,Derek E. Wildman,Derek E. Wildman,Yingqi Xiong,Andrei V. Gudkov,Qiumei Zheng,Gideon Rechavi,Sanyang Liu,Lily Bazak,Jie Chen,Jie Chen,Binyamin A. Knisbacher,Yao Lu,Imad Shams,Krzysztof Gajda,Marta Farré,Jaebum Kim,Harris A. Lewin,Jian Ma,Mark Band,Anne Bicker,Angela Kranz,Tobias Mattheus,Hanno Schmidt,Andrei Seluanov,Jorge Azpurua,Michael R. McGowen,Eshel Ben Jacob,Kexin Li,Shaoliang Peng,Xiaoqian Zhu,Xiangke Liao,Shuai Cheng Li,Anders Krogh,Xin Zhou,Leonid Brodsky,Jun Wang +54 more
TL;DR: In this paper, a Genome-Wide Adaptive Complex to underground stresses in blind mole rats Spalax is described, where the adaptive complexes are based on adaptive complexes to underground stress.