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Xihong Lin
Researcher at Harvard University
Publications - 389
Citations - 32083
Xihong Lin is an academic researcher from Harvard University. The author has contributed to research in topics: Population & Genome-wide association study. The author has an hindex of 76, co-authored 361 publications receiving 26162 citations. Previous affiliations of Xihong Lin include Texas A&M University & University of Washington.
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Estimation of the number of spiked eigenvalues in a covariance matrix by bulk eigenvalue matching analysis
TL;DR: In this article, the authors proposed a method to estimate the number of spiked eigenvalues in the residual covariance matrix, which is assumed to be a diagonal matrix whose entries are drawn from a gamma distribution.
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Accelerated DNA methylation age and the use of antihypertensive medication among older adults.
Xu Gao,Elena Colicino,Jincheng Shen,Allan C. Just,Jamaji C. Nwanaji-Enwerem,Cuicui Wang,Brent A. Coull,Xihong Lin,Pantel S. Vokonas,Yinan Zheng,Lifang Hou,Joel Schwartz,Andrea A. Baccarelli +12 more
TL;DR: It is underlines that DNAmAge and AA may not be able to capture the preventive effects of AHMs that reduce cardiovascular risks and mortality.
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Rare variants in fox-1 homolog A (RBFOX1) are associated with lower blood pressure
Karen Y. He,Heming Wang,Brian E. Cade,Priyanka Nandakumar,Ayush Giri,Erin B. Ware,Jeffrey Haessler,Jingjing Liang,Jennifer A. Smith,Nora Franceschini,Thu H. Le,Charles Kooperberg,Todd L. Edwards,Sharon L.R. Kardia,Xihong Lin,Aravinda Chakravarti,Susan Redline,Xiaofeng Zhu +17 more
TL;DR: The study showed that associations of rare variants could be efficiently detected using family information and identified multiple rare, coding variants in RBFOX1 associated with reduced SBP.
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Genetic associations with neuroendocrine tumor risk: results from a genome-wide association study
Yeting Du,Monica Ter-Minassian,Lauren K. Brais,Nichole V. Brooks,Amanda Waldron,Jennifer A. Chan,Xihong Lin,Peter Kraft,David C. Christiani,Matthew H. Kulke +9 more
TL;DR: Initial evidence is provided that presumed sporadic small intestine neuroendocrine tumors may have a genetic etiology, and the results provide a basis for further exploring the role of genes implicated in this analysis, and for replication studies to confirm the observed associations.
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Smoking History as a Potential Predictor of Immune Checkpoint Inhibitor Efficacy in Metastatic Non-Small Cell Lung Cancer.
Xinan Wang,Biagio Ricciuti,Joao Victor Machado Alessi,Tom C. Nguyen,Mark M. Awad,Xihong Lin,Bruce E. Johnson,David C. Christiani +7 more
TL;DR: In this article, a study was conducted on 644 advanced non-small cell lung cancer (NSCLC) patients treated with ICI monotherapy between April 2013 and September 2020 at the Dana-Farber Cancer Institute and Brigham and Women's Hospital.