Xihong Lin

TL;DR: In this article, the extent to which observed US COVID-19 racial and ethnic disparities can be explained by socioeconomic factors that influence how people live, work, and play, and pre-existing comorbidities.

TL;DR: A generalized linear mixed model is used to analyze the overdispersed binomial data on mutant frequency from the transgenic mouse assay, with a random effect for each level of the sampling hierarchy, to create a comprehensive framework within which different sources of variation in the data can be evaluated in nested factorial experiments and treatment effects can be assessed simultaneously.

TL;DR: RAFFI as mentioned in this paper leverages the efficient RaPID method to call IBD segments first, then estimate the ϕ and π0 from detected IBD segment, which is achieved by a data-driven approach that adjusts the estimation based on phasing quality and genotyping quality.

TL;DR: A structural modeling approach for parameter estimation using the maximum likelihood estimation method and an EM algorithm is developed to calculate maximum likelihood estimators, in which Monte Carlo simulations are used to evaluate the conditional expectations in the E-step.

TL;DR: In this paper, the authors conducted a multi-ethnic genome-wide association study of neck circumference, adjusted and unadjusted for BMI, in up to 15,090 European Ancestry (EA) and African American (AA) individuals.