Y
Yosef Shiloh
Researcher at Tel Aviv University
Publications - 206
Citations - 35738
Yosef Shiloh is an academic researcher from Tel Aviv University. The author has contributed to research in topics: Ataxia-telangiectasia & DNA damage. The author has an hindex of 75, co-authored 200 publications receiving 34100 citations. Previous affiliations of Yosef Shiloh include German Cancer Research Center & Weizmann Institute of Science.
Papers
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Journal ArticleDOI
Many faces of ATM: eighth international workshop on ataxia-telangiectasia.
Journal ArticleDOI
Nuclear poly(A)-binding protein 1 is an ATM target and essential for DNA double-strand break repair
Michal Gavish-Izakson,Bhagya Bhavana Velpula,Ran Elkon,Rosario Prados-Carvajal,Georgina D. Barnabas,Alejandro Pineiro Ugalde,Reuven Agami,Tamar Geiger,Pablo Huertas,Yael Ziv,Yosef Shiloh +10 more
TL;DR: It is established that PABPN1 is recruited to the DDR as a critical regulator of DSB repair, and a novel ATM-dependent axis in the rapidly growing interface between RNA metabolism and the DDR is uncovered.
Journal ArticleDOI
Phenylketonuria: variable phenotypic outcomes of the R261Q mutation and maternal PKU in the offspring of a healthy homozygote.
Sandra E. Kleiman,Lina Vanagaite,Jeanna Bernstein,Gerard Schwartz,Nathan Brand,A. Elitzur,Savio L. C. Woo,Yosef Shiloh +7 more
TL;DR: A family in which two children with severe, classical PKU and their unaffected brother showed mild signs of maternal PKU was studied, suggesting that mutations that do not completely destroy phenylalanine hydroxylase activity may exhibit variable phenotypic expression which is unpredictable.
Book ChapterDOI
Expression and assay of recombinant ATM.
Journal ArticleDOI
The defect in the AT-like hamster cell mutants is complemented by mouse chromosome 9 but not by any of the human chromosomes
W. Jongmans,G. W. C. T. Verhaegh,Nicolaas G. J. Jaspers,Peter Demant,Adayapalam T. Natarajan,Yosef Shiloh,Mitsuo Oshimura,Eric J. Stanbridge,Raghbir S. Athwal,Andrew P. Cuthbert,Robert F. Newbold,Paul H.M. Lohman,Małgorzata Z. Zdzienicka +12 more
TL;DR: The assignment of the mouse homolog of the ATM gene to mouse chromosome 9, and the presence of this mouse chromosome only in the radioresistant hamster cell hybrids suggest that the hamster AT-like mutant are homologous to AT, although they are not complemented by hamster chromosome 11.