Y
Yoshio Momose
Researcher at University of Tokyo
Publications - 12
Citations - 1120
Yoshio Momose is an academic researcher from University of Tokyo. The author has contributed to research in topics: Genetic association & Single-nucleotide polymorphism. The author has an hindex of 9, co-authored 11 publications receiving 1038 citations. Previous affiliations of Yoshio Momose include Osaka University.
Papers
More filters
Journal ArticleDOI
Mutations in COQ2 in familial and sporadic multiple-system atrophy the multiple-system atrophy research collaboration
Jun Mitsui,Takashi Matsukawa,Hiroyuki Ishiura,Yoko Fukuda,Yoko Fukuda,Yaeko Ichikawa,Hidetoshi Date,Budrul Ahsan,Yasuo Nakahara,Yoshio Momose,Yuji Takahashi,Atsushi Iwata,Jun Goto,Yorihiro Yamamoto,Makiko Komata,Katsuhiko Shirahige,Kenju Hara,Akiyoshi Kakita,Mitsunori Yamada,Hitoshi Takahashi,Osamu Onodera,Masatoyo Nishizawa,Hiroshi Takashima,Ryozo Kuwano,Hirohisa Watanabe,Mizuki Ito,Gen Sobue,Hiroyuki Soma,Ichiro Yabe,Hidenao Sasaki,Masashi Aoki,Kinya Ishikawa,Hidehiro Mizusawa,Kazuaki Kanai,Takamichi Hattori,Satoshi Kuwabara,Kimihito Arai,Shigeru Koyano,Yoshiyuki Kuroiwa,Kazuko Hasegawa,Tatsuhiko Yuasa,Kenichi Yasui,Kenji Nakashima,Hijiri Ito,Yuishin Izumi,Ryuji Kaji,Takeo Kato,Susumu Kusunoki,Yasushi Osaki,Masahiro Horiuchi,Tomoyoshi Kondo,Shigeo Murayama,Nobutaka Hattori,Mitsutoshi Yamamoto,Miho Murata,Wataru Satake,Tatsushi Toda,Alexandra Durr,Alexis Brice,Alessandro Filla,Thomas Klockgether,Ullrich Wallner,Garth A. Nicholson,Sid Gilman,Clifford W. Shults,Caroline M. Tanner,Walter A. Kukull,Virginia M.-Y. Lee,Eliezer Masliah,Phillip A. Low,Paola Sandroni,John Q. Trojanowski,Laurie J. Ozelius,Tatiana Foroud,Shoji Tsuji +74 more
TL;DR: Functionally impaired variants of COQ2 were associated with an increased risk of multiple-system atrophy in multiplex families and patients with sporadic disease, providing evidence of a role of impaired COQ1 activities in the pathogenesis of this disease.
Journal ArticleDOI
Multiple candidate gene analysis identifies α-synuclein as a susceptibility gene for sporadic Parkinson's disease
Ikuko Mizuta,Wataru Satake,Yuko Nakabayashi,Chiyomi Ito,Satoko Suzuki,Yoshio Momose,Yoshitaka Nagai,Akira Oka,Hidetoshi Inoko,Jiro Fukae,Yuko Saito,Motoji Sawabe,Shigeo Murayama,Mitsutoshi Yamamoto,Nobutaka Hattori,Miho Murata,Tatsushi Toda +16 more
TL;DR: Findings establish SNCA as a definite susceptibility gene for sporadic PD, a major component of Lewy bodies, the pathological hallmark of PD.
Journal ArticleDOI
Association studies of multiple candidate genes for Parkinson's disease using single nucleotide polymorphisms.
Yoshio Momose,Miho Murata,Kazuhiro Kobayashi,Masaji Tachikawa,Yuko Nakabayashi,Ichiro Kanazawa,Tatsushi Toda +6 more
TL;DR: The results provide genetic evidence supporting a role for BDNF in the pathogenesis of Parkinson's disease and confirm an association with the S18Y polymorphism of the UCH‐L1 gene.
Journal ArticleDOI
Multiplex Families With Multiple System Atrophy
Kenju Hara,Yoshio Momose,S. Tokiguchi,Mitsuteru Shimohata,Kenshi Terajima,Osamu Onodera,Akiyoshi Kakita,Mitsunori Yamada,Hitoshi Takahashi,Motoyuki Hirasawa,Yoshikuni Mizuno,Katsuhisa Ogata,Jun Goto,Ichiro Kanazawa,Masatoyo Nishizawa,Shoji Tsuji +15 more
TL;DR: Findings in these multiplex families suggest the presence of familial MSA with autosomal recessive inheritance and a genetic predisposition to MSA.
Journal ArticleDOI
Variants associated with Gaucher disease in multiple system atrophy
Jun Mitsui,Takashi Matsukawa,Hidenao Sasaki,Ichiro Yabe,Masaaki Matsushima,Alexandra Durr,Alexis Brice,Hiroshi Takashima,Akio Kikuchi,Masashi Aoki,Hiroyuki Ishiura,Tsutomu Yasuda,Hidetoshi Date,Budrul Ahsan,Atsushi Iwata,Jun Goto,Yaeko Ichikawa,Yasuo Nakahara,Yoshio Momose,Yuji Takahashi,Kenju Hara,Akiyoshi Kakita,Mitsunori Yamada,Hitoshi Takahashi,Osamu Onodera,Masatoyo Nishizawa,Hirohisa Watanabe,Mizuki Ito,Gen Sobue,Kinya Ishikawa,Hidehiro Mizusawa,Kazuaki Kanai,Takamichi Hattori,Satoshi Kuwabara,Kimihito Arai,Shigeru Koyano,Yoshiyuki Kuroiwa,Kazuko Hasegawa,Tatsuhiko Yuasa,Kenichi Yasui,Kenji Nakashima,Hijiri Ito,Yuishin Izumi,Ryuji Kaji,Takeo Kato,Susumu Kusunoki,Yasushi Osaki,Masahiro Horiuchi,Tomoyoshi Kondo,Shigeo Murayama,Nobutaka Hattori,Mitsutoshi Yamamoto,Miho Murata,Wataru Satake,Tatsushi Toda,Alessandro Filla,Thomas Klockgether,Ullrich Wüllner,Garth A. Nicholson,Sid Gilman,Caroline M. Tanner,Walter A. Kukull,Mathew B. Stern,Virginia M.-Y. Lee,John Q. Trojanowski,Eliezer Masliah,Phillip A. Low,Paola Sandroni,Laurie J. Ozelius,Tatiana Foroud,Shoji Tsuji +70 more
TL;DR: In this paper, the role of GBA variants in multiple system atrophy (MSA) was investigated in a large case-control series, and the results indicated that, as in PD and DLB, GBA-causing variants are associated with MSA.