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Yu-Jui Yvonne Wan
Researcher at University of California, Davis
Publications - 216
Citations - 7784
Yu-Jui Yvonne Wan is an academic researcher from University of California, Davis. The author has contributed to research in topics: Retinoid X receptor & Retinoic acid. The author has an hindex of 46, co-authored 208 publications receiving 6874 citations. Previous affiliations of Yu-Jui Yvonne Wan include Drexel University & University of California, Berkeley.
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Journal ArticleDOI
Retinoid pathway and cancer therapeutics.
Nathan Bushue,Yu-Jui Yvonne Wan +1 more
TL;DR: This review summarizes the current understanding of how retinoids are processed and act with an emphasis on the application of retinoid in cancer treatment and prevention.
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Hepatocyte-Specific Mutation Establishes Retinoid X Receptor α as a Heterodimeric Integrator of Multiple Physiological Processes in the Liver
Yu-Jui Yvonne Wan,Dahsing An,Yan Cai,Joyce J. Repa,Tim H.-P. Chen,Monica Flores,Catherine Postic,Mark A. Magnuson,Ju Chen,Kenneth R. Chien,Samuel W. French,David J. Mangelsdorf,Henry M. Sucov +12 more
TL;DR: The presence of a complex circuitry in which RXRα is integrated into a number of diverse physiological pathways as a common regulatory component of cholesterol, fatty acid, bile acid, steroid, and xenobiotic metabolism and homeostasis is demonstrated.
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Modulation of experimental alcohol-induced liver disease by cytochrome P450 2E1 inhibitors☆
M. Morimoto,Ann Louise Hagbjork,Yu-Jui Yvonne Wan,Paul Fu,Paolo Clot,Emanuele Albano,Magnus Ingelman-Sundberg,Samuel W. French +7 more
TL;DR: The data support the idea that there is a link between CYP2E1 induction by ethanol and the early phase of ethanol-induced liver injury in this rat model, which may involve lipid peroxidation and p-nitrophenol hydroxylase activity.
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Serotonin transporter polymorphisms and adverse effects with fluoxetine treatment.
Roy H. Perlis,David Mischoulon,Jordan W. Smoller,Yu-Jui Yvonne Wan,Stefania Lamon-Fava,Keh Ming Lin,Jerrold F. Rosenbaum,Maurizio Fava +7 more
TL;DR: The "S" allele of the 5HTTLPR may identify patients at risk for developing insomnia or agitation with fluoxetine treatment, and this preliminary result requires confirmation in larger samples.
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Human carboxylesterases HCE1 and HCE2: Ontogenic expression, inter-individual variability and differential hydrolysis of oseltamivir, aspirin, deltamethrin and permethrin
TL;DR: A large inter-individual variability was detected in mRNA, protein, protein and hydrolytic activity within the same age group, particularly in the fetal and child groups, and this has important pharmacological and toxicological implications.