Z
Zaïna Aït Arkoub
Researcher at Pierre-and-Marie-Curie University
Publications - 4
Citations - 860
Zaïna Aït Arkoub is an academic researcher from Pierre-and-Marie-Curie University. The author has contributed to research in topics: Gene & Antigen. The author has an hindex of 2, co-authored 2 publications receiving 813 citations.
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Journal ArticleDOI
Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover
Jorge R. Almeida,David Price,David Price,Laura Papagno,Zaïna Aït Arkoub,Delphine Sauce,Ethan Bornstein,Tedi E. Asher,Assia Samri,Aurélie Schnuriger,Ioannis Theodorou,Dominique Costagliola,Christine Rouzioux,Henri Agut,Anne-Geneviève Marcelin,Daniel C. Douek,Brigitte Autran,Victor Appay +17 more
TL;DR: It is shown that B27-KK10–specific CD8+ T cells are characterized by polyfunctional capabilities, increased clonal turnover, and superior functional avidity, which constitute the basis for effective control of HIV-1 replication.
Journal ArticleDOI
A Molecular Basis for the Control of Preimmune Escape Variants by HIV-Specific CD8(+) T Cells.
Kristin Ladell,Masao Hashimoto,Maria Candela Iglesias,Pascal G. Wilmann,James E. McLaren,Stephanie Gras,Takayuki Chikata,Nozomi Kuse,Solène Fastenackels,Emma Gostick,John S. Bridgeman,Vanessa Venturi,Zaïna Aït Arkoub,Henri Agut,David van Bockel,Jorge R. Almeida,Jorge R. Almeida,Daniel C. Douek,Laurence Meyer,Alain Venet,Masafumi Takiguchi,Jamie Rossjohn,Jamie Rossjohn,David Price,David Price,Victor Appay +25 more
TL;DR: It is found that cross-reactive CD8+ T cell clonotypes were mobilized to counter the rapid emergence of HIV-1 variants that can directly affect T cell receptor (TCR) recognition in HLA-B∗2705+ individuals.
Journal ArticleDOI
Two novel variations p.(Ser1275Thr) and p.(Ser1275Arg) in FLT4 causing prenatal hereditary lymphedema type 1
Yosra Lajmi,Laurence Loeuillet,Giulia Petrilli,Charles Egloff,Juliette Nectoux,Clémence Molac,Nathalie Roux,Emmanuelle Pannier,Amale Achaiaa,Zaïna Aït Arkoub,Sophie Chuon,Aurélie Coussement,Jean-Michel Dupont,Valérie Malan,Emmanuel Spaggiari,Ferechté Razavi,Jeanne Amiel,Bettina Bessières,Sarah Grotto,Tania Attié-Bitach +19 more
TL;DR: Hereditary lymphedema 1 is a rare congenital condition characterized by the development of chronic swelling in body parts as discussed by the authors , which is highly variable in expression and age of onset with different presentations.
Journal ArticleDOI
A wave of deep intronic mutations in X-linked Alport Syndrome.
Marie Boisson,Christelle Arrondel,Nicolas Cagnard,Vincent Morinière,Zaïna Aït Arkoub,Hassan Saei,Laurence Heidet,Jessica Kachmar,Aurélie Hummel,Bertrand Knebelmann,Marie-Noëlle Bonnet-Dupeyron,Bertrand Isidor,Hassane Izzedine,Eric Legrand,Philippe Couarch,Olivier Gribouval,Christine Bole-Feysot,Mélanie Parisot,Patrick Nitschke,Corinne Antignac,G. Dorval +20 more
TL;DR: In this paper , the authors used a transcriptomic approach to identify causative events in a group of 19 patients with X-linked Alport syndrome (XLAS) without identified mutation by Alport gene panel sequencing.