Showing papers by "Annamalai University published in 2008"

Identification of major sources controlling groundwater chemistry from a hard rock terrain - A case study from Mettur taluk, Salem district, Tamil Nadu, India

Abstract: The study area Mettur forms an important industrial town situated NW of Salem district. The geology of the area is mainly composed of Archean crystalline metamorphic complexes. To identify the major process activated for controlling the groundwater chemistry an attempt has been made by collecting a total of 46 groundwater samples for two different seasons, viz., pre-monsoon and post-monsoon. The groundwater chemistry is dominated by silicate weathering and (Na + Mg) and (Cl + SO4) accounts of about 90% of cations and anions. The contribution of (Ca + Mg) and (Na + K) to total cations and HCO3 indicates the domination of silicate weathering as major sources for cations. The plot for Na to Cl indicates higher Cl in both seasons, derived from Anthropogenic (human) sources from fertilizer, road salt, human and animal waste, and industrial applications, minor representations of Na also indicates source from weathering of silicate-bearing minerals. The plot for Na/Cl to EC indicates Na released from silicate weathering process which is also supported by higher HCO3 values in both the seasons. Ion exchange process is also activated in the study area which is indicated by shifting to right in plot for Ca + Mg to SO4 + HCO3. The plot of Na-Cl to Ca + Mg-HCO3-SO4 confirms that Ca, Mg and Na concentrations in groundwater are derived from aquifer materials. Thermodynamic plot indicates that groundwater is in equilibrium with kaolinite, muscovite and chlorite minerals. Saturation index of silicate and carbonate minerals indicate oversaturation during pre-monsoon and undersaturation during post-monsoon, conforming dissolution and dilution process. In general, water chemistry is guided by complex weathering process, ion exchange along with influence of Cl ions from anthropogenic impact.

Influences of tool pin profile and axial force on the formation of friction stir processing zone in AA6061 aluminium alloy

Abstract: AA6061 aluminium alloy (Al-Mg-Si alloy) has gathered wide acceptance in the fabrication of light weight structures requiring a high strength-to-weight ratio and good corrosion resistance. Compared to the fusion welding processes that are routinely used for joining structural aluminium alloys, the friction stir welding (FSW) process is an emerging solid state joining process in which the material that is being welded does not melt and recast. This process uses a non-consumable tool to generate frictional heat in the abutting surfaces. The welding parameters such as tool rotational speed, welding speed, axial force etc., and the tool pin profile plays a major role in deciding the weld quality. In this investigation an attempt has been made to understand the effect of axial force and tool pin profiles on FSP zone formation in AA6061 aluminium alloy. Five different tool pin profiles (straight cylindrical, tapered cylindrical, threaded cylindrical, triangular and square) have been used to fabricate the joints at three different axial force levels. The formation of FSP zone has been analysed macroscopically. Tensile properties of the joints have been evaluated and correlated with the FSP zone formation. From this investigation it is found that the square tool pin profile produces mechanically sound and metallurgically defect free welds compared to other tool pin profiles.

Role of curcumin in health and disease

Abstract: Curcumin (diferuloylmethane) is an orange-yellow component of turmeric (Curcuma longa), a spice often found in curry powder. In recent years, considerable interest has been focused on curcumin due to its use to treat a wide variety of disorders without any side effects. It is one of the major curcuminoids of turmeric, which impart its characteristic yellow colour. It was used in ancient times on the Indian subcontinent to treat various illnesses such as rheumatism, bodyache, skin diseases, intestinal worms, diarrhoea, intermittent fevers, hepatic disorders, biliousness, urinary discharges, dyspepsia, inflammations, constipation, leukoderma, amenorrhea, and colic. Curcumin has the potential to treat a wide variety of inflammatory diseases including cancer, diabetes, cardiovascular diseases, arthritis, Alzheimer's disease, psoriasis, etc, through modulation of numerous molecular targets. This article reviews the use of curcumin for the chemoprevention and treatment of various diseases.

Probiotics in aquaculture: importance and future perspectives

Abstract: Aquaculture is one of the fastest developing growth sectors in the world and Asia presently contributes about 90% to the global production. However, disease outbreaks are constraint to aquaculture production thereby affects both economic development of the country and socio-economic status of the local people in many countries of Asia-Pacifi c region. Disease control in aquaculture industry has been achieved by following different methods using traditional ways, synthetic chemicals and antibiotics. However, the use of such expensive chemotherapeutants for controlling diseases has been widely criticized for their negative impacts like accumulation of residues, development of drug resistance, immunosuppressants and reduced consumer preference for aqua products treated with antibiotics and traditional methods are ineffective against controlling new diseases in large aquaculture systems. Therefore, alternative methods need to be developed to maintain a healthy microbial environment in the aquaculture systems there by to maintain the health of the cultured organisms. Use of probiotics is one of such method that is gaining importance in controlling potential pathogens. This review provides a summary of the criteria for the selection of the potential probiotics, their importance and future perspectives in aquaculture industry.

An Interesting Correlation between Crystalline Perfection and Second Harmonic Generation Efficiency on KCl-and Oxalic Acid-Doped ADP Crystals

Abstract: The effect of dopants (over a concentration range from 1 to 10 mol %), namely KCl and oxalic acid (C2H2O4·2H2O, Oxa), on the growth process, crystalline perfection, and nonlinear optical (NLO) properties of ammonium dihydrogen phosphate (NH4H2PO4, ADP) single crystals grown by a slow evaporation solution growth technique has been investigated. The high-resolution X-ray diffraction (HRXRD) studies used to evaluate crystalline perfection reveal some interesting features on the ability of accommodating the dopants by the crystalline matrix. The remarkable and systematic increase in the broadness and asymmetry of the diffraction curves as the concentration increases clearly indicates that the dopants predominantly occupied the interstitial positions in the crystalline matrix. Due to the larger size of the Oxa molecule, the crystalline matrix could not accommodate these dopants, which led to the formation of a very low angle (tilt angle <1′) internal structural grain boundaries at high concentrations. The rela...

Relationship between base metal properties and friction stir welding process parameters

Abstract: Friction stir welding (FSW) is a solid state welding process for joining aluminum alloys and has been employed in aerospace, rail, automotive and marine industries for joining aluminium, magnesium, zinc and copper alloys. In FSW, the base metal properties such as yield strength, ductility and hardness control the plastic flow of the material under the action of rotating non-consumable tool. The FSW process parameters such as tool rotational speed, welding speed, axial force, etc. play a major role in deciding the weld quality. In this investigation, an attempt has been made to establish relationship between the base material properties and FSW process parameters. FSW joints have been made using five different grades of aluminium alloys (AA1050, AA6061, AA2024, AA7039 and AA7075) using different combinations of process parameters. Macrostructural analysis has been done to check the weld quality (defective or defect free). Empirical relationships have been established between base metal properties and tool rotational speed and welding speed, respectively. The developed empirical relationships can be effectively used to predict the FSW process parameters to fabricate defect free welds.

Recent Trends in the Production, Purification and Application of Lactic Acid

Abstract: Lactic acid, a naturally occurring multifunctional organic acid, is a valuable industrial chemical used as an acidulant, preservative in the food industry, pharmaceutical, leather, and textile industries, as well as a chemical feedstock. One of the most promising applications of lactic acid is its use for biodegradable and biocompatible lactate polymers, such as polylactic acid. Lactic acid can be produced either by fermentation or by chemical synthesis but the biotechnological fermentation process has received significant importance due to environmental concerns, use of renewable resources instead of petrochemicals, low production temperature, low energy requirements and high purity. There are numerous investigations on the development of biotechnological methods for lactic acid production, with an ultimate objective to enable the process to be more efficient and economical. This review discusses the various recent fermentation technologies to produce lactic acid, different microorganisms involved in the production of lactic acid, purification and wide industrial applications of lactic acid.

Resveratrol enhances GLUT-4 translocation to the caveolar lipid raft fractions through AMPK/Akt/eNOS signalling pathway in diabetic myocardium.

Abstract: Homeostasis of blood glucose by insulin involves stimulation of glucose uptake by translocation of glucose transporter Glut-4 from intracellular pool to the caveolar membrane system In this study we examined resveratrol (RSV)-mediated Glut-4 translocation in the streptozotocin (STZ)-induced diabetic myocardium The rats were randomized into three groups: Control (Con), Diabetes Mellitus (DM) (STZ 65 mg/kg bw, ip) & DM + RSV (25 mg/kg bwt for 2 weeks orally) (RSV) Isolated rat hearts were used as per the experimental model RSV induced glucose uptake was observed in vitro with H9c2 cardiac myoblast cells Decreased blood glucose level was observed after 30 days (375 mg/dl) in RSV-treated rats when compared to DM (587 mg/dl) Treatment with RSV demonstrated increased Adenosine Mono Phosphate Kinase (AMPK) phosphorylation compared to DM Lipid raft fractions demonstrated decreased expression of Glut-4, Cav-3 (04, 06-fold) in DM which was increased to 075-and 11-fold on RSV treatment as compared to control Increased Cav-1 expression (14-fold) in DM was reduced to 07-fold on RSV treatment Increased phosphorylation of endothelial Nitric Oxide Synthase (eNOS) & Akt was also observed in RSV compared to DM (P< 005) Confocal microscopy and co-immunoprecipitation studies demonstrated decreased association of Glut-4/Cav-3 and increased association of Cav-1/eNOS in DM as compared to control and converse results were obtained on RSV treatment Our results suggests that the effect of RSV is non-insulin dependent and triggers some of the similar intracellular insulin signalling components in myocardium such as eNOS, Akt through AMPK pathway and also by regulating the caveolin-1 and caveolin-3 status that might play an essential role in Glut-4 translocation and glucose uptake in STZ- induced type-1 diabetic myocardium

Inhibition of monoamine oxidase-B by the polyphenolic compound, curcumin and its metabolite tetrahydrocurcumin, in a model of Parkinson's disease induced by MPTP neurodegeneration in mice.

Abstract: We investigated the effects of the polyphenolic compound curcumin and its metabolite tetrahydrocurcumin (ThC), in the model of Parkinson's disease induced in mice by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). In this model depletion of dopamine(DA) and DOPAC (3,4-dihydroxy phenyl acetic acid)) occurs with increased monoamine oxidase (MAO-B) activity. We used HPLC with electrochemical detection to measure DA and DOPAC respectively while MAO-B was assayed by spectroflourimetry using the conversion of the fluorogenic substrate, kyuramine. Systemic administration of curcumin (80 mg/kg i. p.) and tetrahydrocurcumin (60 mg/kg i. p.) significantly reversed the MPTP-induced depletion of DA and DOPAC. The MAO-B activity was also significantly inhibited by these compounds. The results showed that curcumin and tetrahydrocurcumin reversed the MPTP induced depletion of DA and DOPAC which may in part be due to inhibition of MAO-B activity. In conclusion, both curcumin and its metabolite ThC exert neuroprotection against MPTP induced neurotoxicity.

Seasonal variations in physico-chemical characteristics of water, sediment and soil texture in arid zone mangroves of Kachchh-Gujarat.

Abstract: The present study was carried out to determine the physicochemical characteristics of water and sediment and the textural aspects of sediments in western mangroves of Kachchh-Gujarat, west coast of India, for a period of two years during 1999-2000. Surface water and sediment temperatures varied from 17 o C to 37 o C and from 18.4 o C to 37 o C respectively. Tidal amplitude varied from 0.03m to 3.78 m. Salinity varied from 34.0 to 44 ‰ and the pH in water and sediment ranged between 7.0 and 8.9 and 6.29 and 8.45 respectively. Variation in dissolved oxygen content was from 3.42 to 5.85 ml l -1 . Concentrations of nutrients viz. nitrate (0.23 to 7.26 4M), nitrite (0.04 to 0.874M), phosphate (0.13 to 3.12 4M) and reactive silicate (4.23 to 19.02 4M) also varied independently. Total organic carbon varied from 0.29% to 2.56% and the total inorganic phosphorus ranged between 0.12 mg g -1 and 1.97 mg g -1 . Total nitrogen varied from 0.02 mg g -1 to 1.95 mg g -1 . Sediment textures ranges in terms of % of sand, clay and silt were: 0.26-19.2; 7.6-47 and 47-87.4 respectively in all the 3 stations. The nature of soil texture is characterized by the abundance of silty loam, silty clay and silty clay loam.

Effect of Tool Pin Profile and Tool Rotational Speed on Mechanical Properties of Friction Stir Welded AA6061 Aluminium Alloy

Abstract: AA6061 aluminium alloy (Al-Mg-Si alloy) has gathered wide acceptance in the fabrication of light weight structures requiring a high strength-to-weight ratio and good corrosion resistance. Compared to many of the fusion welding processes that are routinely used for joining structural aluminium alloys, the Friction Stir Welding (FSW) process is an emerging solid state joining process in which the material that is being welded does not melt and recast. This process uses a nonconsumable tool to generate frictional heat in the abutting surfaces. The welding parameters such as tool rotational speed, welding speed, axial force, etc., and tool pin profile play a major role in deciding the joint properties. In this investigation, an attempt has been made to study the effect of rotational speed and tool pin profile on mechanical properties of AA6061 aluminium alloy. Five different tool pin profiles (straight cylindrical, tapered cylindrical, threaded cylindrical, triangular, and square) have been used to fabricate ...

Production and characterization of a glycolipid biosurfactant from Bacillus megaterium using economically cheaper sources

Abstract: Criteria selected for screening of biosurfactant production by Bacillus megaterium were hemolytic assay, bacterial cell hydrophobicity and the drop-collapse test. The data on hemolytic activity, bacterial cell adherence with crude oil and the drop-collapse test confirmed the biosurfactant-producing ability of the strain. Accordingly, the strain was cultured at different temperatures, pH values, salinity and substrate (crude oil) concentration in mineral salt medium to establish the optimum culture conditions, and it was shown that 38°C, 2.0% of substrate concentration, pH 8.0 and 30‰ of salt concentration were optimal for maximum growth and biosurfactant production. Laboratory scale biosurfactant production in a fermentor was done with crude oil and cheaper carbon sources like waste motor lubricant oil and peanut oil cake, and the highest biosurfactant production was found with peanut oil cake. Characterization of partially purified biosurfactant inferred that it was a glycolipid with emulsification potential of waste motor lubricant oil, crude oil, peanut oil, diesel, kerosene, naphthalene, anthracene and xylene.

The essential oil of Zingiber officinalis Linn (Zingiberaceae) as a mosquito larvicidal and repellent agent against the filarial vector Culex quinquefasciatus Say (Diptera: Culicidae).

Abstract: Essential oils extracted by steam distillation from Zingiber officinalis was evaluated for larvicidal and repellent activity against the filarial mosquito Culex quinquefasciatus. The larval mortality was observed after 24 h treated for late third instar. The LC50 value was 50.78 ppm. Skin repellent test at 1.0, 2.0, 3.0, and 4.0 mg/cm2 concentration of Z. officinalis gave 100% protection up to 15, 30, 60, and 120 min. These results clearly reveal that the essential oil of Z. officinalis served as a potential larvicidal and repellent agent against filarial vector C. quinquefasciatus.