British Hospital

About: British Hospital is a healthcare organization based out in Montevideo, Uruguay. It is known for research contribution in the topics: Population & Hazard ratio. The organization has 445 authors who have published 358 publications receiving 7878 citations. The organization is also known as: British Hospital.

Visual field examination during transient migrainous visual loss.

Abstract: A transient episode of bilateral amaurosis fugax, or transient visual loss, occurred in a patient with ophthalmic migraine associated with mitral valve prolapse while computerized visual field testing was performed. This fortunate finding illustrated characteristic defects which are compared with the patient's visual field tested 24 hours later. Statistical analysis of both examinations is stressed here.

Influence of DFNB1 status on expressive language in deaf children with cochlear implants.

Abstract: ObjectiveThe objective of this study was to compare the language growth of children with connexin-related deafness (DFNB1) who received cochlear implants versus the language growth of implanted children with non-DFNB1 deafness.Study DesignA prospective longitudinal observational study and analysis.S

Clinical parameters, LysoGb3, podocyturia, and kidney biopsy in children with Fabry disease: is a correlation possible?

Abstract: Fabry disease is an X-linked lysosomal storage disorder caused by α-galactosidase enzyme deficiency. We present clinical, biochemical, and histologic findings in children with classical phenotypic presentation of Fabry disease. A retrospective analysis was performed using charts from 14 children with confirmed diagnosis. Clinical parameters were evaluated. Globotriaosylsphingosine -lysoGb3- detection in plasma, podocyturia, and kidney biopsy were carried out in all cases. All patients except one demonstrated at least one symptom of Fabry disease. LysoGb3 levels were above the normal range in all patients. Podocyturia was documented in all patients. Kidney biopsy revealed glomerular, interstitial, vascular, and tubular changes on light microscopy in nearly all patients. Electron microscopy showed podocyte inclusions in all patients. No difference in symptomatology was discernible between boys and girls. Podocyturia was detectable in children serving as a possible early marker of kidney injury. LysoGb3 was elevated in all cases, emphasizing the importance for diagnosis especially in female patients with normal αGal A activity. A possible association between lysoGb3 and symptom severity and histological involvement in kidney biopsy should be assessed in prospective studies with enough statistical power to determine if lysoGb3 can be used to predict nephropathy in children with Fabry disease.

Osteosynthesis of diaphyseal fractures of the radius and ulna using an internal fixator (PC-Fix). A prospective study.

Abstract: Over a five year period, 121 forearm shaft fractures in 82 patients including nine non unions were fixed using the PC-Fix. Two patients died early; of the remaining 80 patients (119 bones) 96% were followed until bone healing. No non unions or late infections were observed in spite of the fact that no primary bone grafts were used except when treating non unions. In this clinical study with a high follow up rate using a newly developed internal fixator, encouraging overall results were achieved and the technology of monocortical locked screws was proven to be valid.