Catholic University of Daegu

About: Catholic University of Daegu is a education organization based out in Gyeongsan-si, South Korea. It is known for research contribution in the topics: Population & Apoptosis. The organization has 2745 authors who have published 5670 publications receiving 80311 citations.

Multi-center study on migraine and seizure-related headache in patients with epilepsy

Abstract: Purpose The purpose of this study is to investigate the frequency and characteristics of migraine and seizure-related headache (SRH) according to the criteria of the International Headache Society. Materials and Methods A questionnaire was undertaken at the initial evaluation of newly referred patients from 32 epilepsy clinics. Results Of a total of 597 patients, 74 (12.4%) patients had migraine. Age at the onset of epilepsy was lower in patients with migraine than in those without. Twenty-six (4.4%), nine (1.5%), and 146 (24.5%) patients experienced prodromal, ictal, and postictal SRH, respectively (n = 169, 28.3%). A pain intensity of prodromal and postictal SRH was 6.1 ± 1.5 (SD) and 6.3 ± 1.9 (SD) on the visual analogue scale, and their duration was 12.6 ± 26.7 (SD) hours and 9.0 ± 17.4 (SD) hours, respectively. Age at the onset of epilepsy was lower in patients with SRH than in those without, and the risk of occurrence of SRH was significantly greater in patients with longer epilepsy duration. SRH could be classified as a type of migraine in 46.2% of patients with prodromal SRH and in 36.3% of patients with postictal SRH. Prodromal SRH occurred more frequently and was more likely to be a migraine-type in patients with migraine compared with those without. Postictal SRH occurred more frequently and was more likely to be a migraine-type in patients with migraine. Conclusion This study suggests that SRH is a frequent accompanying symptom of epileptic seizures causing major impairment in daily life, and migraine is an important comorbidity of epilepsy, affecting the incidence and characteristics of SRH.

Substance P upregulates osteoclastogenesis by activating nuclear factor kappa B in osteoclast precursors.

Abstract: Conclusion SP upregulates osteoclastogenesis by activating NF-κB in osteoclast precursors. Objective Osteoclastic bone resorption is a common finding of otitis media with or without cholesteatoma. Factors upregulating osteoclastogenesis are implicated in bone resorption. The aim of this study was to investigate the effect of substance P (SP) on mouse osteoclastogenesis in vitro. Material and Methods The SP dose response was analyzed in a mouse osteoclast culture induced by macrophage colony-stimulating factor and receptor activator for nuclear factor kappa B (NF-κB) ligand. Western blot analysis was performed to elucidate the subcellular target of SP in osteoclastogenesis. Results Treatment with SP significantly increased osteoclastogenesis compared to control. SP activated nuclear translocation of NF-κB, which is an essential event in osteoclastogenesis in osteoclast precursors (bone marrow macrophages).

Chitosan-soybean oil emulsion coating affects physico-functional and sensory quality of eggs during storage

Abstract: Effects of soybean oil (SO) and chitosan-soybean oil (CH:SO = 40:60) emulsion as coating materials for preserving internal quality of eggs were evaluated during 7 and 15 weeks storage at 25 °C and 4 °C, respectively. Consumers (n = 150) assessed surface properties and purchase intent of freshly coated eggs. Noncoated eggs deteriorated from AA to B grade after 1 week while coated eggs retained A grade up to 5 weeks at 25 °C. Amongst coatings, CH:SO emulsion maintained a lower albumen pH while SO was better at reducing weight loss. Effect of refrigeration on albumen pH was minimal. Weight loss of coated eggs was