Northern Illinois University

About: Northern Illinois University is a education organization based out in DeKalb, Illinois, United States. It is known for research contribution in the topics: Large Hadron Collider & Population. The organization has 8818 authors who have published 20008 publications receiving 632341 citations. The organization is also known as: NIU.

Aspergillus nidulans VeA subcellular localization is dependent on the importin a carrier and on light

Abstract: Summary The veA gene is a light-dependent regulator govern- ing development and secondary metabolism in Aspergillus nidulans. We have identified a putative bipartite nuclear localization signal (NLS) motif in the A. nidulans VeA amino acid sequence and demon- strated its functionality when expressed in yeast. Furthermore, migration of VeA to the nucleus was dependent on the importin a. This bipartite NLS is also functional when VeA is expressed in A. nidulans. Interestingly, we found that VeA migration to the nucleus is light-dependent. While in the dark VeA is located mainly in the nuclei, under light VeA is found abundantly in the cytoplasm. The VeA1 mutant protein (lacking the first 36 amino acids at the N-terminus) was found predominantly in the cyto- plasm independent of illumination. This indicates that the truncated bipartite NLS in VeA1 is not functional and fails to respond to light. These results might explain the lack of the morphological light-dependent response in strains carrying the veA1 allele. We also evaluated the effect of light on production of the myc- otoxin sterigmatocystin in a veA wild-type and the veA1 mutant strains and found that the highest amount of toxin was produced by the veA+ strain growing in the dark, condition favouring accumula- tion of VeA in the nucleus.

Volcanism and Geochemistry in Central America: Progress and Problems

Abstract: Most Central American volcanoes occur in an impressive volcanic front that trends parallel to the strike of the subducting Cocos Plate. The volcanic front is a chain, made of right-stepping, linear segments, 100 to 300 Km in length. Volcanoes cluster into centers, whose spacing is random but averages about 27 Km. These closely spaced, easily accessible volcanic centers allow mapping of geochemical variations along the volcanic front. Abundant back-arc volcanoes in southeast Guatemala and central Honduras allow two cross-arc transects. Several element and isotope ratios (e.g. Ba/La, U/Th, B/La, 10 Be/ 9 Be, 87 Sr/ 86 Sr) that are thought to signal subducted marine sediments or altered MORB consistently define a chevron pattern along the arc, with its maximum in Nicaragua. Ba/La, a particularly sensitive signal, is 130 at the maximum in Nicaragua but decreases out on the limbs to 40 in Guatemala and 20 in Costa Rica, which is just above the nominal mantle value of 15. This high amplitude regional variation, roughly symmetrical about Nicaragua, contrasts with the near constancy, or small gradient, in several plate tectonic parameters such as convergence rate, age of the subducting Cocos Plate, and thickness and type of subducted sediment. The large geochemical changes over relatively short distances make Central America an important margin for seeking the tectonic causes of geochemical variations; the regional variation has both a high amplitude and structure, including flat areas and gradients. The geochemical database continues to improve and is already adequate to compare to tectonic models with length scales of 100 Km or longer.

Search for the Standard Model Higgs boson produced in association with top quarks and decaying into bb¯ in pp collisions at √s = 8 TeV with the ATLAS detector

Abstract: A search for the Standard Model Higgs boson produced in association with a top-quark pair, , is presented. The analysis uses 20.3 fb(-1) of pp collision data at , collected with the ATLAS detector at the Large Hadron Collider during 2012. The search is designed for the decay mode and uses events containing one or two electrons or muons. In order to improve the sensitivity of the search, events are categorised according to their jet and b-tagged jet multiplicities. A neural network is used to discriminate between signal and background events, the latter being dominated by +jets production. In the single-lepton channel, variables calculated using a matrix element method are included as inputs to the neural network to improve discrimination of the irreducible background. No significant excess of events above the background expectation is found and an observed (expected) limit of 3.4 (2.2) times the Standard Model cross section is obtained at 95 % confidence level. The ratio of the measured signal cross section to the Standard Model expectation is found to be assuming a Higgs boson mass of 125 Gev.

Efficient use of commodity futures in diversified portfolios

Abstract: We provide evidence on the role of commodity futures in portfolios comprised of stocks, bonds, T-bills, and real estate. Over the period investigated (1973–1997), Markowitz optimization over a range of risk levels gives substantial weight to commodity futures, thereby enhancing the portfolios’ returns. We find dramatically different results when we use a simple ex ante measure of monetary stringency to dichotomize the sample into expansive-versus-restrictive monetary-policy periods. In periods characterized by restrictive monetary policy, commodity futures are shown to have substantial weight in the efficient portfolios, with significant return enhancement at all levels of risk. In periods characterized by expansive monetary policy, commodity futures are shown to have little or no weight in the efficient portfolios, with no return enhancement at all levels of risk. © 2000 John Wiley & Sons, Inc. Jrl Fut Mark 20:489–506, 2000