Institution
Ochsner Medical Center
Healthcare•New Orleans, Louisiana, United States•
About: Ochsner Medical Center is a healthcare organization based out in New Orleans, Louisiana, United States. It is known for research contribution in the topics: Population & Medicine. The organization has 980 authors who have published 1159 publications receiving 49961 citations. The organization is also known as: Ochsner Hospital & Ochsner Foundation Hospital.
Papers published on a yearly basis
Papers
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TL;DR: In the presence of ascites noted by echocardiography, the FL is usually noted within the ascites, but the FL will be noted most often in the subcostal window only.
Abstract: Figure 1. The falciform ligament (falc. lig.: horizontal black arrow) connects the parietal peritoneum with the anterior surface of the liver. It obliquely attaches to the abdominal surface of the diaphragm (white arrow denotes attachment site). Note the close proximity of the falciform ligament with the diaphragmatic surface of the pericardium (pericardial sac: vertical black arrow). (Reproduced and modified with permission from Reference 4). of the liver denotes the junction of its right and left lobes.1,2 Following the FL from the liver superiorly reveals it to end transversely into the abdominal surface of the diaphragm.3 Anatomically, the diaphragmatic surface of the pericardium lies in close proximity to the FL (Fig. 1). In the presence of ascites noted by echocardiography, the FL is usually noted within the ascites. Ascites is visualized from both parasternal and subcostal windows,5 but the FL will be noted most often in the subcostal window only.
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TL;DR: An 8-month-old, African American male presented with 4 days of increased work of breathing and had symmetrical weakness of the upper and lower extremities, and the patient was unable to sit up unassisted.
Abstract: An 8-month-old, African American male presented with 4 days of increased work of breathing. The boy was previously healthy according to his mother but had received no medical care since birth. The patient’s regular diet consisted of breast milk and a minimal amount of pureed baby food. Vital signs revealed a blood pressure of 96/49 mm Hg, heart rate of 124 beats per minute, respiratory rate of 30 breaths per minute, and oxygen saturation of 85%. The patient was afebrile. He weighed 7.2 kg (<3rd percentile) and measured 66 cm in length (3rd percentile). On physical examination, the patient was awake, alert, and in no acute distress. Cardiac examination revealed regular rate and rhythm, muffled first and second heart sounds, and no additional heart sounds. Brachial and femoral pulses were 2/2 bilaterally. Good air exchange was noted bilaterally, but the patient did have intermittent wheezing and subcostal retractions. Abdominal examination showed mild hepatomegaly. Widened wrists were noted. There was symmetrical weakness of the upper and lower extremities, and the patient was unable to sit up unassisted. Initial laboratory values were notable for hemoglobin of 7.1 g/dL (normal = 10.5-13.5 g/dL) and hematocrit of 25.2% (normal = 33% to 39%) with a mean corpuscular volume of 55.4 fL (normal = 70-86 fL). Iron studies were consistent with iron-deficiency anemia. Serum calcium and phosphorus were 7.1 mg/dL (normal = 8.7-10.5 mg/dL) and 3.6 mg/dL (normal = 4.5-6.7 mg/ dL), respectively. Serum parathyroid hormone level was 1471 pg/mL (normal = 10-65 pg/mL). Serum albumin was within normal limits. Alkaline phosphatase was 1256 IU/L (normal = 82-383 IU/L). A chest x-ray revealed cardiomegaly and pulmonary edema (Figure 1). Electrocardiogram revealed T-wave inversion in the lateral leads and a prolonged corrected QT interval, and an echocardiogram demonstrated a severely dilated left ventricle with poor systolic function (ejection fraction of 10% to 20%; Figure 2). His brain natriuretic peptide level was markedly elevated at 1253 pg/mL (normal = 0-99 pg/mL). 586057 CPJXXX10.1177/0009922815586057Clinical PediatricsMcEachern et al research-article2015
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TL;DR: A 13-year-old African American male was referred to the pediatric hematology/oncology clinic by the orthopedic oncologist with the chief complaint of enlarging right hand mass, painful mass in his right axilla, and associated shoulder pain for the past 6 months.
Abstract: A 13-year-old African American male was referred to the pediatric hematology/oncology clinic by the orthopedic oncologist with the chief complaint of enlarging right hand mass, painful mass in his right axilla, and associated shoulder pain for the past 6 months. Review of systems was unremarkable with no report of fever, weight loss, and respiratory or cardiovascular abnormalities. Examination of the right hand showed a firm 4 cm × 3 cm mass in the first web space with right axillary and supraclavicular lymphadenopathy. Rest of the examination was normal. Magnetic resonance imaging (MRI; Figure 1) revealed a T2-enhancing heterogeneous mass measuring 2.8 × 4.3 × 1.9 cm in the hypothenar region of the right hand without evidence of invasion of adjacent structures. A computed tomography (CT) scan of chest, abdomen, and pelvis showed only enlarged nodes in the right axilla. Biopsy confirmed rhabdomyosarcoma (RMS) alveolar subtype. His bone marrow revealed infiltration with RMS. A diagnosis of alveloar RMS stage IV was confirmed. Following the biopsy, bone marrow, and central line placement on hospital day 1, he complained of loss of function of his lower extremities and developed urinary retention. Neurological exam revealed 0-1/5 strength bilaterally, diminished reflexes, and loss of sensation to light touch and pinprick on both lower extremities.
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TL;DR: A restricted T cell repertoire that is maintained over time is observed in the setting of lung transplantation, and the molecular profile mirrors the restricted clonal T cell infiltrates seen in autoimmune disease.
Abstract: the identical T cell profile was maintained over time from a few months up to two years between sequential biopsy samples. The Fox P3 immunohistochemistry stain demonstrated staining of 10 to 15% of the infiltrate. Conclusions: A restricted T cell repertoire that is maintained over time is observed in the setting of lung transplantation. The molecular profile mirrors the restricted clonal T cell infiltrates seen in autoimmune disease. Regulatory T cells may play some role in reducing the extent of the emerging clonal T cell infiltrates; he main implicated cell in biopsies of cellular rejection are not of the regulatory T cell subset. The nature of the T cell epitope specifically in regards to self-antigen versus alloantigen remains to be determined.
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Authors
Showing all 993 results
Name | H-index | Papers | Citations |
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Carl J. Lavie | 106 | 1135 | 49318 |
Michael R. Jaff | 82 | 442 | 28891 |
Michael F. O'Rourke | 81 | 451 | 35355 |
Mandeep R. Mehra | 80 | 644 | 31939 |
Richard V. Milani | 80 | 454 | 23410 |
Christopher J. White | 77 | 621 | 25767 |
Bruce A. Reitz | 74 | 333 | 18457 |
Robert C. Bourge | 69 | 273 | 24397 |
Sana M. Al-Khatib | 69 | 377 | 17370 |
Hector O. Ventura | 66 | 478 | 16379 |
Andrew Mason | 63 | 360 | 15198 |
Aaron S. Dumont | 60 | 386 | 13020 |
Philip J. Kadowitz | 55 | 379 | 11951 |
David W. Dunn | 54 | 195 | 8999 |
Lydia A. Bazzano | 51 | 267 | 13581 |