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Tien-Jyun Chang

Researcher at National Taiwan University

Publications -  53
Citations -  3323

Tien-Jyun Chang is an academic researcher from National Taiwan University. The author has contributed to research in topics: Type 2 diabetes & Diabetes mellitus. The author has an hindex of 20, co-authored 47 publications receiving 2953 citations. Previous affiliations of Tien-Jyun Chang include Eastern Virginia Medical School.

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Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.

Anubha Mahajan, +395 more
- 01 Mar 2014 - 
TL;DR: In this paper, the authors aggregated published meta-analyses of genome-wide association studies (GWAS), including 26,488 cases and 83,964 controls of European, east Asian, south Asian and Mexican and Mexican American ancestry.
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Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians

Yoon Shin Cho, +72 more
- 01 Jan 2012 - 
TL;DR: The combined analysis identified eight new T2D loci reaching genome-wide significance, which mapped in or near GLIS3, PEPD, FITM2-R3HDML-HNF4A, KCNK16, MAEA, GCC1-PAX4, PSMD6 and ZFAND3, which may regulate glucose-dependent insulin secretion in the pancreas.
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Common variation in the fat mass and obesity-associated (FTO) gene confers risk of obesity and modulates BMI in the Chinese population.

Yi-Cheng Chang, +8 more
- 01 Aug 2008 - 
TL;DR: Genetic variation in the FTO gene is strongly associated with obesity and BMI in the Chinese population, but its effect size on BMI is comparable with that in the European population.
Journal Article

Association study of the genetic polymorphisms of the transcription factor 7-like 2 (TCF7L2) gene and type 2 diabetes in the Chinese population. Commentary

Mark O. Goodarzi, +8 more
- 01 Jan 2007 - 
TL;DR: In this article, the effect of the TCF7L2 polymorphisms in a Han Chinese population was explored, and the association of SNPs and haplotypes with type 2 diabetes and linkage disequilibrium (LD) structure was analyzed.
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Association study of the genetic polymorphisms of the transcription factor 7-like 2 (TCF7L2) gene and type 2 diabetes in the Chinese population.

Yi-Cheng Chang, +6 more
- 01 Oct 2007 - 
TL;DR: The data suggested that the TCF7L2 genetic polymorphisms are major determinants for risk of type 2 diabetes in the Chinese population, which may attribute to the low frequencies of these two SNPs.