Institution
Universiti Sains Malaysia
Education•George Town, Pulau Pinang, Malaysia•
About: Universiti Sains Malaysia is a education organization based out in George Town, Pulau Pinang, Malaysia. It is known for research contribution in the topics: Population & Ring (chemistry). The organization has 23231 authors who have published 39356 publications receiving 655434 citations. The organization is also known as: USM & University of Science, Malaysia.
Papers published on a yearly basis
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TL;DR: The data indicate that honey can inhibit carcinogenesis by modulating the molecular processes of initiation, promotion, and progression stages, and may serve as a potential and promising anticancer agent which warrants further experimental and clinical studies.
Abstract: Honey is a natural product known for its varied biological or pharmacological activities-ranging from anti-inflammatory, antioxidant, antibacterial, antihypertensive to hypoglycemic effects This review article focuses on the role of honey in modulating the development and progression of tumors or cancers It reviews available evidence (some of which is very recent) with regards to the antimetastatic, antiproliferative and anticancer effects of honey in various forms of cancer These effects of honey have been thoroughly investigated in certain cancers such as breast, liver and colorectal cancer cell lines In contrast, limited but promising data are available for other forms of cancers including prostate, bladder, endometrial, kidney, skin, cervical, oral and bone cancer cells The article also underscores the various possible mechanisms by which honey may inhibit growth and proliferation of tumors or cancers These include regulation of cell cycle, activation of mitochondrial pathway, induction of mitochondrial outer membrane permeabilization, induction of apoptosis, modulation of oxidative stress, amelioration of inflammation, modulation of insulin signaling and inhibition of angiogenesis Honey is highly cytotoxic against tumor or cancer cells while it is non-cytotoxic to normal cells The data indicate that honey can inhibit carcinogenesis by modulating the molecular processes of initiation, promotion, and progression stages Thus, it may serve as a potential and promising anticancer agent which warrants further experimental and clinical studies
168 citations
TL;DR: Phytochemical screening of E. hirta leaf extract revealed the presence of reducing sugars, terpenoids, alkaloids, steroids, tannins, flavanoids and phenolic compounds.
168 citations
TL;DR: The activated carbon prepared under optimum conditions was mesoporous with BET surface area of 1141 m(2)/g, total pore volume of 0.6 cm(3)/g and average pore diameter of 2.5 nm, and the surface morphology and functional groups of the activated carbon were respectively determined from the scanning electron microscopy and Fourier transform infrared analysis.
168 citations
TL;DR: In this paper, the effect of the coupling agent on the curing and physical properties of the vulcanizates has been investigated using γ-mercapto-propyltrimethoxysilane.
168 citations
TL;DR: Antioxidant and α-amylase inhibitor peptides were successfully extracted from Pinto bean protein isolate (PBPI) using Protamex using a factorial design experiment and the effects of extraction time, pH and temperature were studied.
168 citations
Authors
Showing all 23437 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Peter J. Anderson | 120 | 966 | 63635 |
| B.H. Hameed | 106 | 328 | 39456 |
| Abdul Rahman Mohamed | 84 | 542 | 23633 |
| Muhammad Iqbal | 77 | 961 | 23821 |
| Xiao-Zeng You | 73 | 763 | 22917 |
| Keat Teong Lee | 71 | 276 | 16745 |
| Rajeev Singh | 69 | 365 | 17805 |
| Abdul Latif Ahmad | 68 | 490 | 22012 |
| Hiroyuki Osada | 67 | 651 | 18192 |
| Mohammad Jawaid | 65 | 503 | 19471 |
| Subhash Bhatia | 63 | 204 | 12804 |
| Mohammed Farid | 61 | 299 | 15820 |
| Thurasamy Ramayah | 57 | 388 | 12103 |
| Colleen Ward | 56 | 173 | 17494 |
| Robert R. Twilley | 55 | 166 | 11745 |