University of Guadalajara

About: University of Guadalajara is a education organization based out in Guadalajara, Mexico. It is known for research contribution in the topics: Population & Context (language use). The organization has 13040 authors who have published 17399 publications receiving 168085 citations. The organization is also known as: UdeG & UdG.

A novel bio-inspired optimization model based on Yellow Saddle Goatfish behavior.

Abstract: Several species of fish live in groups to increase their foraging efficiency and reproduction rates. Such groups are considered self-organized since they can adopt different cooperative actions without the presence of an apparent leader. One of their most interesting collaborative behaviors found in fish is the hunting strategy presented by the Yellow Saddle Goatfish (Parupeneus cyclostomus). In this strategy, the complete group of fish is distributed in subpopulations to cover the whole hunting region. In each sub-population, all fish participate collectively in the hunt considering two different roles: chaser and blocker. In the hunt, a chaser fish actively tries to find the prey in a certain area whereas a blocker fish moves spatially to avoid the escape of the prey. In this paper, we develop the hunting model of Yellow Saddle Goatfish, which at some abstraction level can be characterized as a search strategy for optimization proposes. In the approach, different computational operators are designed in order to emulate this peculiar hunting behavior. With the use of this biological model, the new search strategy improves the optimization results in terms of accuracy and convergence in comparison to other popular optimization techniques. The performance of this method is tested by analyzing its results with other related evolutionary computation techniques. Several standard benchmark functions commonly used in the literature were considered to obtain optimization results. Furthermore, the proposed model is applied to solve certain engineering optimization problems. Analysis of the experimental results exhibits the efficiency, accuracy, and robustness of the proposed algorithm.

DNA damage in mouse lymphocytes exposed to curcumin and copper

Abstract: Dietary polyphenolics, such as curcumin, have shown antioxidant and anti-inflammatory effects Some antioxidants cause DNA strand breaks in excess of transition metal ions, such as copper The aim of this study was to evaluate thein vitro effect of curcumin in the presence of increasing concentrations of copper to induce DNA damage in murine leukocytes by the comet assay Balb-C mouse lymphocytes were exposed to 50 μM curcumin and various concentrations of copper (10 μM, 100 μM and 200 μM) Cellular DNA damage was detected by means of the alkaline comet assay Our results show that 50 μM curcumin in the presence of 100–200 μM copper induced DNA damage in murine lymphocytes Curcumin did not inhibit the oxidative DNA damage caused by 50 μM H2O2 in mouse lymphocytes Moreover, 50 μM curcumin alone was capable of inducing DNA strand breaks under the tested conditions The increased DNA damage by 50 μM curcumin was observed in the presence of various concentrations of copper, as detected by the alkaline comet assay