Institution
University of Peradeniya
Education•Kandy, Sri Lanka•
About: University of Peradeniya is a education organization based out in Kandy, Sri Lanka. It is known for research contribution in the topics: Population & Poison control. The organization has 5970 authors who have published 7388 publications receiving 197002 citations.
Topics: Population, Poison control, Adsorption, Electrolyte, Agriculture
Papers published on a yearly basis
Papers
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TL;DR: In this article, the regeneration of soil fertility through agronomic measures would be a useful and easily adoptable method of enhancing productivity of tropical Asian upland small-holding farming units.
Abstract: Smallholder cropping systems are a vital component in the agricultural sectors of tropical Asia, especially in the developing nations. These systems are important for producing food and providing a livelihood to a major proportion of the populations of Asia. While the rice systems, usually cultivated under puddled conditions are considered stable, the upland or highland units, which provide a range of food, fibre and feed commodities, are generally situated on marginal lands. Low soil fertility, erosion, sub-optimal crop management and subsistence farming conditions characterize these units. Hence, these units require improved but low cost strategies to reverse the trend of lower productivity, loss of sustainability and most importantly, the loss of livelihood for the farming populations. Among the many strategies available, the regeneration of soil fertility through agronomic measures would be a useful and easily adoptable method of enhancing productivity of tropical Asian upland small-holding farming units. The methods available include the revival of age-old traditions such as adding organic matter directly to soils, green manuring and mimicking forest ecosystems through agrofor-estry. Agronomic measures using plants to enrich the soil and regenerate its supporting capacity are presented in the present paper. Relevant examples are cited to highlight the potential of these methods for regenerating productivity of the upland smallholder farming units and more importantly the agro-based livelihood of a large majority of the populations of tropical Asia.
43 citations
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TL;DR: An approach to fulfilling this need via combining the scientific, technological and economical resources from Costa Rica and the United States with the knowledge and talent of Sri Lanka, poly-specific snake antivenom has been initiated, coordinated and funded by Animal Venom Research International (AVRI), a nonprofit charity.
43 citations
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TL;DR: A color chart can be used to give a clinically useful quantitative estimate of methemoglobinemia to be used in settings of limited resources and showed good agreement with spectrometric measurements.
43 citations
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TL;DR: The non-antimicrobial properties of tetracyclines such as anti-inflammatory, proanabolic and anti-catabolic actions make them effective pharmaceuticals for the adjunctive management of chronic inflammatory diseases as discussed by the authors.
Abstract: The non-antimicrobial properties of tetracyclines such as anti-inflammatory, proanabolic and anti-catabolic actions make them effective pharmaceuticals for the adjunctive management of chronic inflammatory diseases. An over-exuberant inflammatory response to an antigenic trigger in periodontitis and other chronic inflammatory diseases could contribute to an autoimmune element in disease progression. Their adjunctive use in managing periodontitis could have beneficial effects in curbing excessive inflammatory loading from commonly associated comorbidities such as CHD, DM and arthritis. Actions of tetracyclines and their derivatives include interactions with MMPs, tissue inhibitors of MMPs, growth factors and cytokines. They affect the sequence of inflammation with implications on immunomodulation, cell proliferation and angiogenesis; these actions enhance their scope, in treating a range of disease entities. Non-antimicrobial chemically modified tetracyclines (CMTs) sustain their diverse actions in organ systems which include anti-inflammatory, anti-apoptotic, anti-proteolytic actions, inhibition of angiogenesis and tumor metastasis. A spectrum of biological actions in dermatitis, periodontitis, atherosclerosis, diabetes, arthritis, inflammatory bowel disease, malignancy and prevention of bone resorption is particularly relevant to minocycline. Experimental models of ischemia indicate their specific beneficial effects. Parallel molecules with similar functions, improved Zn binding and solubility have been developed for reducing excessive MMP activity. Curbing excessive MMP activity is particularly relevant to periodontitis, and comorbidities addressed here, where specificity is paramount. Unique actions of tetracyclines in a milieu of excessive inflammatory stimuli make them effective therapeutic adjuncts in the management of chronic inflammatory disorders. These beneficial actions of tetracyclines are relevant to the adjunctive management of periodontitis subjects presenting with commonly prevalent comorbidities addressed here.
43 citations
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TL;DR: It is confirmed that ischemic strokes can occur following envenoming by D. russelii and involvement of multiple medium to large vessel territories and absence of watershed infarctions points to prothrombotic properties of the venom as the putative mechanism.
43 citations
Authors
Showing all 5992 results
Name | H-index | Papers | Citations |
---|---|---|---|
David Gunnell | 114 | 688 | 79867 |
Michael S. Roberts | 82 | 740 | 27754 |
Richard F. Gillum | 77 | 217 | 84184 |
Lakshman P. Samaranayake | 75 | 586 | 19972 |
Adrian C. Newton | 74 | 453 | 21814 |
Nick Jenkins | 71 | 325 | 22477 |
Michael Eddleston | 63 | 310 | 16762 |
Velmurugu Ravindran | 63 | 280 | 14057 |
Samath D Dharmaratne | 62 | 151 | 103916 |
Nicholas A. Buckley | 62 | 419 | 14283 |
Saman Warnakulasuriya | 60 | 282 | 15766 |
Keith W. Hipel | 58 | 543 | 14045 |
Geoffrey K. Isbister | 57 | 468 | 12690 |
Fiona J Charlson | 53 | 91 | 80274 |
Abbas Shafiee | 51 | 418 | 8679 |