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Institution

Worcester Foundation for Biomedical Research

About: Worcester Foundation for Biomedical Research is a based out in . It is known for research contribution in the topics: Estrone & Estrogen. The organization has 2195 authors who have published 2646 publications receiving 115809 citations. The organization is also known as: Worcester Foundation for Experimental Biology.
Topics: Estrone, Estrogen, RNA, Sperm, Microtubule


Papers
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Journal ArticleDOI
TL;DR: The stereochemistry of the dehydrogenation, with the isotope exchange and with the probable mechanisms of these two reactions which are believed to be intimately related are concerned.

64 citations

Journal ArticleDOI
TL;DR: The nucleus raphe dorsalis is organized as a reticular nucleus with neurons having few, straight and poorly ramified dendrites with the most striking age-related changes in the multipolar and ovoid-shaped cells.

64 citations

Journal ArticleDOI
TL;DR: Suspensions of dimyristoyl and dipalmitoyl phosphatidylcholine vesicles bearing 10 to 40 (w/w)% cholesterol inhibited the fertilizing ability of uterine-capacitated rabbit spermatozoa at concentrations of 1 to 10 mg of lipid/ml.
Abstract: SummarySuspensions of dimyristoyl and dipalmitoyl phosphatidylcholine vesicles bearing 10 to 40 (w/w)% cholesterol inhibited the fertilizing ability of uterine-capacitated rabbit spermatozoa at concentrations of 1 to 10 mg of lipid/ml. Recovery of fertilizing ability by treated sperm cells was observed following insemination into the uterus 5 to 6 hr before ovulation. Vesicles lacking the sterol were not inhibitory under the conditions employed. Suspensions of cholesterol (0.4 to 4 mg of sterol/ml) without phospholipid, in contrast, inhibited fertilization. Implication of cholesterol in sperm decapacitation by seminal plasma membrane vesicles is discussed in terms of these results.I am indebted to Mr. R. Byrne and Mrs. N. Davis for their helpful assistance. The electron micrographs were prepared by Mr. K. Bedigian. Financial support was received from NIH Contract No. 1-HD-3-2781.

64 citations

Journal ArticleDOI
TL;DR: EtOH-induced decreases in plasma AVP levels can be explained by EtOH's inhibition of calcium currents in the nerve terminals, with significant reductions in 10 mM EtOH.

64 citations

Journal ArticleDOI
TL;DR: In this article, aufklarung der Struktur von 19-Oxy-Δ4-androsten-3,17-dion (VI), einer Substanz, isoliert nach Inkubation von Δ4-Androsten 3,17dion and von Dehydroepiandrosteron with einem Rinder-Nebennieren-Homogenat, ist beschrieben.
Abstract: Die Aufklarung der Struktur von 19-Oxy-Δ4-androsten-3,17-dion (VI), einer Substanz, isoliert nach Inkubation von Δ4-Androsten-3,17-dion und von Dehydroepiandrosteron mit einem Rinder-Nebennieren-Homogenat, ist beschrieben. Dies ist unseres Wissens die erste Beobachtung der Hydroxylierungin vitro einer angularen Methylgruppe eines Steroids. Mehrere Folgerungen sind erortert.

64 citations


Authors

Showing all 2195 results

NameH-indexPapersCitations
Robert A. Weinberg190477240903
Harvey F. Lodish165782101124
E. J. Corey136137784110
Peter Palese13252657882
Sten Orrenius13044757445
Aldons J. Lusis12767373786
Michel Goedert12533764671
Frederic D. Bushman11944284206
Robert H. Singer11339141493
Joel F. Habener11242743774
Ryuzo Yanagimachi10243840651
Jaak Panksepp9944640748
Hagan Bayley9734433575
John H. Hartwig9626030336
Joseph Avruch9419140946
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20191
20171
20091
20087
20063
20042