Zonguldak Karaelmas University

About: Zonguldak Karaelmas University is a based out in . It is known for research contribution in the topics: Population & Copolymer. The organization has 1939 authors who have published 4296 publications receiving 62466 citations.

Comparison of contrast sensitivity and visual acuity between deep anterior lamellar keratoplasty and penetrating keratoplasty in patients with keratoconus.

Abstract: AIM To evaluate postoperative visual acuity and contrast sensitivity results following deep anterior lamellar keratoplasty (DALK) and penetrating keratoplasty (PK) in patients with keratoconus (KC).

Is Mean Platelet Volume a Reliable Marker to Predict Ischemic Stroke in the Follow-Up of Patients with Carotid Stenosis?

Abstract: Background The objective of the study is to evaluate the reliability of mean platelet volume (MPV) for predicting ischemic stroke (cerebrovascular event [CVE]) among patients with different degrees of carotid stenosis. Methods Fifty-two patients with CVEs, 136 patients with carotid artery disease (CAD), and 40 healthy volunteers were enrolled in this study. All participants were divided into the following groups according to CAD: absence of stenosis, less than 50% stenosis, 50%-69% stenosis, and 70% or more to total occlusion of the internal carotid artery. For each participant, the parameters of CAD were assessed using ultrasonography. To obtain the values of CRP and MPV and the leukocyte and platelet counts, all samples were processed within 30 minutes after blood collection. Univariate and multivariate analyses were used to evaluate the association between the values of serum C-reactive protein (CRP) and MPV and carotid stenosis. Results In terms of age and gender, there was no statistically significant difference between the groups ( P = .094 and P = .428, respectively). However, CRP values in patients with CAD and CVEs were significantly higher than those in the controls ( P P = .249). Moreover, the MPV values did not show any significant difference between the groups ( P = .053) and among the patients with CAD ( P = .64). There was no positive correlation between serum CRP and MPV values in patients with CAD regarding the degree of carotid stenosis ( r = .061, P = .477). Conclusion The findings of this study claim that MPV has no predictive value during follow-up of the patients with CAD for CVEs.

The Role of Retrotransposons in Gene Family Expansions in the Human and Mouse Genomes.

Abstract: NextGenProject [CZ.1.07/2.3.00/20.0303]; Charles University in Prague Institutional Research Support [SVV 260 208/2015]; National Cancer Institute at the National Institutes of Health [U54 CA143924, P30 CA23074]; American Cancer Society [74-001-34-IRG]; Czech National Grid Infrastructure MetaCentrum running under the program "Projects of Large Research, Development, and Innovations Infrastructures" [CESNET LM2015042]

N-Acetyl-Cysteine Improves Anastomotic Wound Healing after Radiotherapy in Rats

Abstract: Aim: This study was designed to determine the effects of intraperitoneally or orally administered N-acetylcysteine (NAC) on anastomotic healing of irradiated rats. Methods: Thirty-two male Wistar a...