Showing papers in "Archives of Oral Biology in 1999"
••
TL;DR: It was concluded that tubule orientation has no appreciable effect on the elastic behaviour of normal dentine, and that the elastic properties of healthy dentine can be modelled as an isotropic continuum with a Young's modulus of approx.
261 citations
••
TL;DR: It is demonstrated that TGF-beta1 and -beta3 can stimulate secretion of extracellular matrix by odontoblasts, are mitogenic to pulp cells, and that T GF-beta3 may have inductive effects on pulpal cells.
214 citations
••
TL;DR: Results indicate that a cytokine network is activated in the periapex in response to bacterial infection, and that Th1-modulated pro-inflammatory pathways may predominate during periapical bone destruction.
200 citations
••
TL;DR: The results suggest that the growth factor TGF-alpha and certain cytokines are associated with the presence of periodontal disease.
154 citations
••
TL;DR: Whether a correlation exists between microhardness (MH) and transversal microradiographical (TMR) data for in situ-induced caries lesions in irradiated and nonirradiated human enamel is evaluated.
152 citations
••
TL;DR: A power function optimally described the relation between muscle work per chew and the mechanical measurements of food; this confirmed that the masticatory process is adjusted to accommodate to food texture.
152 citations
••
TL;DR: Results suggest that mRNA for both pro- and anti-inflammatory cytokines, i.e., mixed T-helper 1 (TH1) and TH2 cytokine profiles, are generated simultaneously by a limited number of cells in chronic lesions of OLP.
125 citations
••
TL;DR: Salivary antioxidant power may affect individual sensitivity toward tobacco stress, and smoking of a single cigarette induced a significant reduction in glutathione concentration, which was significantly higher in smokers.
114 citations
••
TL;DR: Craniofacial morphology could be a result of far more contributing factors than previously believed, and linear regression analysis failed to demonstrate any significant association between bite force and facial morphology among men and women.
110 citations
••
TL;DR: The role of minor salivary glands in the function and defence of the oral cavity may be better understood as a result of new physiological and molecular methods applicable to samples of limited size and availability.
108 citations
••
TL;DR: Experiments suggest that clinical isolates of A. actinomycetemcomitans possess unique binding properties that promote adsorption to and impede desorption from SHA, and may resemble attachment described for several biofilm-forming, non-oral pathogens.
••
TL;DR: Three-dimensional, dynamic model used to predict active and passive jaw-muscle tensions during simulated postural rest, jaw opening and chewing appears to provide a useful conceptual framework for developing hypotheses regarding the role of muscle tensions during human jaw function.
••
TL;DR: The effects of agents that inhibit Gtfs in solution and adsorbed to a surface were explored, indicating that the nature of the inhibitor is important, and also whether the Gtf enzyme is in solution or adsorbing to saliva-coated hydroxylapatite.
••
TL;DR: It was concluded that, although collected at the same time of the day, pH, buffer capacity and concentrations of calcium and phosphate in unstimulated whole saliva in the single individual vary so much that characterization of individuals and of their saliva based on a single salivary analysis is unreliable and hazardous.
••
TL;DR: With ageing, the intensity of the fluorescence increased whereas the decay time decreased, suggesting that the increase in fluorescence intensity was partially due to a temperature-dependent physicochemical mechanism.
••
TL;DR: It was concluded that the vertical mandibular posture is more open during sleep in patients with OSA than in healthy adults and thatMandibular opening increases progressively during apnoeic episodes and decreases at the termination of those episodes.
••
TL;DR: The results suggest that MMP-1 and cathepsin K are important in root resorption during tooth movement in a mode similar to bone resOrption.
••
TL;DR: It is demonstrated that chewing is associated with general circulatory effects proportional to the bolus resistance, and perceived fatigue was proportional toThe level of muscle activity.
••
TL;DR: It is suggested that IGF-I might have a primary role in the growth and differentiation of pulp cells in serum-free culture conditions.
••
TL;DR: It is concluded that the canine temporomandibular joint disc can be represented as a linear viscoelastic material, and that it plays an important part as a stress absorber under compression.
••
TL;DR: Preliminary observations in both NOD mice and Sjögren's syndrome patients is that antibody directed against the cell surface muscarinic/cholinergic receptors appears to play an important part in the onset of clinical disease.
••
TL;DR: Application of the small-fibre excitant and inflammatory irritant mustard oil or the excitatory amino-acid receptor agonist glutamate to the rat temporomandibular joint (TMJ) region evokes similar changes in jaw-muscle activity, suggesting that peripheral application of glutamate may be nociceptive.
••
TL;DR: The notion that the lateral pterygoid provides the principal driving force for moving the jaw forwards or laterally in protrusive or lateral excursive condylar movements is supported and suggests that the muscle plays a part in the fine control of jaw movements.
••
TL;DR: The main differences in composition between labial gland saliva and that from the major glands are the higher and variable sodium concentration, the very low phosphate and hydrogen carbonate concentrations, and the higher protein concentration despite low concentrations of amylase.
••
TL;DR: Damaged oral mucosa in patients with oral cancer might allow the new bacterial colonization on the surface and subsequently drain the bacteria into the regional lymph nodes as well as the general circulation.
••
TL;DR: Indomethacin increases ALP activity and the accumulation of mineralized tissue in MC3T3-E1 cells, presumably by inhibiting the production of PGE2, and could signal the suppression of mineralization as early as confluence.
••
TL;DR: The results suggest that low levels of contraction induce a clear haemodynamic response, even at 5% effort, in human masseter and temporalis, and that variation in architecture between the two muscles contributes to these differences in blood flow.
••
TL;DR: SLPI is a major but not sole inhibitor of this virus in saliva, focusing on secretory leucocyte protease inhibitor (SLPI), a 12-kDa mucosal protein that blocks HIV infection in several cell-culture systems.
••
TL;DR: In this article, the effect of NOs inhibitor and scavenger on the secretory response was compared functionally, in the two glands, and the histochemical and functional results both suggest that NO plays an excitatory role in the regulation of parasympathetic nerve-induced salivary secretion in the rat submandibular gland, but not in the sublingual gland.
••
TL;DR: Earlier indications of local production of plasminogen activators and their inhibitors in gingival tissues are confirmed, and the results demonstrate that t-PA and PAI-2 in these patients are produced predominantly in the epithelial tissues.