Journal•ISSN: 0273-2300
Regulatory Toxicology and Pharmacology
Elsevier BV
About: Regulatory Toxicology and Pharmacology is an academic journal published by Elsevier BV. The journal publishes majorly in the area(s): Toxicity & Medicine. It has an ISSN identifier of 0273-2300. Over the lifetime, 4632 publications have been published receiving 138997 citations. The journal is also known as: RTP & R.T.P..
Topics: Toxicity, Medicine, Population, Risk assessment, Biology
Papers published on a yearly basis
Papers
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TL;DR: This paper evaluates several approaches to allow the relative potency of the different PAHs to be considered in a site-specific risk assessment and presents a modified version that it feels more accurately reflects the state of knowledge on the Relative potency of these compounds.
2,339 citations
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TL;DR: The survey results support the value of in vivo toxicology studies to predict for many significant HTs associated with pharmaceuticals and have helped to identify HT categories that may benefit from improved methods.
1,699 citations
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TL;DR: A newly developed probabilistic model, the Creme RIFM model, is used to estimate aggregate exposure to fragrance ingredients using the example of 2-phenylethanol (PEA) to demonstrate the utility of the model in determining systemic and dermal exposure to fragrances from individual products, and aggregate exposure.
1,108 citations
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TL;DR: The data and modelling methods presented show potential as a means of performing ingredient safety assessments for personal care and cosmetics products, and the robustness and ability to estimate aggregate consumer product exposure are presented.
1,057 citations
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TL;DR: The Creme RIFM model offers a very comprehensive and powerful tool for estimating aggregate exposure to fragrance ingredients, suggesting that deterministic models overestimate exposure by 11.5–25 fold.
1,050 citations