Journal ArticleDOI
A novel blood plasma analysis technique combining membrane electrophoresis with silver nanoparticle-based SERS spectroscopy for potential applications in noninvasive cancer detection
Juqiang Lin,Rong Chen,Shangyuan Feng,Jianji Pan,Yongzeng Li,Guannan Chen,Min Cheng,Zufang Huang,Yun Yu,Haishan Zeng +9 more
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TLDR
The gastric cancer group can be unambiguously distinguished from the normal group in this initial test, with both diagnostic sensitivity and specificity of 100%.About:
This article is published in Nanomedicine: Nanotechnology, Biology and Medicine.The article was published on 2011-10-01. It has received 142 citations till now. The article focuses on the topics: Blood proteins & Silver nanoparticle.read more
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Silver Nanoparticles: Therapeutical Uses, Toxicity, and Safety Issues
Carolina Alves dos Santos,Marcelo Martins Seckler,Avinash P. Ingle,Indarchand Gupta,Indarchand Gupta,Stefania Galdiero,Massimiliano Galdiero,Aniket Gade,Mahendra Rai +8 more
TL;DR: This review aims to discuss AgNPs applied in biomedicine and as promising field for insertion and development of new compounds related to medical and pharmacy technology and addresses drug delivery, toxicity issues, and the safety rules concerning biomedical applications of silver nanoparticles.
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Surface-enhanced Raman scattering in cancer detection and imaging.
TL;DR: The progress in SERS for cancer diagnostics, including multiplexed detection and identification of new biomarkers, single-nucleotide polymorphisms, and circulating tumor cells, is summarized and the potential of SERS agents for targeted drug delivery and photothermal therapy is highlighted.
Journal ArticleDOI
Bacteriagenic silver nanoparticles: synthesis, mechanism, and applications.
TL;DR: Bacterial synthesis of extra- and intracellular AgNPs has been reported using biomass, supernatant, cell-free extract, and derived components, and the extracellular mode of synthesis is preferred over the intrACEllular mode owing to easy recovery of nanoparticles.
Journal ArticleDOI
Raman Spectroscopy of Blood and Blood Components
TL;DR: The literature in the field is reviewed, the published Raman spectroscopy studies of erythrocytes, leucocytes, platelets, plasma, and whole blood are collated, and general conclusions on the state of the field are drawn.
Journal ArticleDOI
Rapid identification by surface-enhanced Raman spectroscopy of cancer cells at low concentrations flowing in a microfluidic channel.
TL;DR: A detection platform that combines microfluidics with surface-enhanced Raman spectroscopy (SERS) for the identification of individual mammalian cells continuously flowing in a microfluids channel is described and two deconvolution strategies are examined.
References
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Journal ArticleDOI
Anomalously intense Raman spectra of pyridine at a silver electrode
TL;DR: Anomalously intense Raman spectra of pyridine at a silver electrode was reported in this article, where the Raman spectrum was shown to have a high Raman intensity.
Journal ArticleDOI
A New Type of Secondary Radiation
TL;DR: In this article, it was shown that in every case in which light is scattered by the molecules in dust-free liquids or gases, the diffuse radiation of the ordinary kind, having the same wave-length as the incident beam, is accompanied by a modified scattered radiation of degraded frequency.
Journal ArticleDOI
A New Method for Fast Preparation of Highly Surface-Enhanced Raman Scattering (SERS) Active Silver Colloids at Room Temperature by Reduction of Silver Nitrate with Hydroxylamine Hydrochloride
Nicolae Leopold,Bernhard Lendl +1 more
TL;DR: In this article, a very effective and simple way to produce silver colloids for surface-enhanced Raman scattering (SERS) is reported. But this method is not suitable for the use of SERS in high-dimensional data.
Journal ArticleDOI
Femtomolar detection of prostate-specific antigen: an immunoassay based on surface-enhanced Raman scattering and immunogold labels.
TL;DR: A novel reagent for low-level detection in immunoadsorbent assays is described and the extension of the method to multianalyte assays (e.g., the simultaneous determination of the many complexed forms of PSA) is discussed.
Journal ArticleDOI
Diagnosing breast cancer by using Raman spectroscopy
Abigail S. Haka,Karen Shafer-Peltier,Maryann Fitzmaurice,Joseph P. Crowe,Ramachandra R. Dasari,Michael S. Feld +5 more
TL;DR: The excellent results demonstrate that Raman spectroscopy has the potential to be applied in vivo to accurately classify breast lesions, thereby reducing the number of excisional breast biopsies that are performed.
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A New Method for Fast Preparation of Highly Surface-Enhanced Raman Scattering (SERS) Active Silver Colloids at Room Temperature by Reduction of Silver Nitrate with Hydroxylamine Hydrochloride
Nicolae Leopold,Bernhard Lendl +1 more