Journal ArticleDOI
A rating scale for extrapyramidal side effects
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TLDR
A modification of an earlier rating scale for extrapyramidal system disturbance is described, and evidence for the validity and reliability of the scale is presented.Abstract:
SUMMARY
A modification of an earlier rating scale for extrapyramidal system disturbance is described, and evidence for the validity and reliability of the scale is presented. The usefulness of the scale in studies of neuroleptic drugs is discussed. By its application it is possible to quantify extrapyramidal side effects and to separate them into four principal factors.read more
Citations
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Journal ArticleDOI
The St. Hans Rating Scale for extrapyramidal syndromes: reliability and validity.
Gerlach J,Korsgaard S,P. Clemmesen,A.-M. Lund Lauersen,Magelund G,Noring U,U. J. Povlsen,Per Bech,Daniel E. Casey +8 more
TL;DR: The St. Hans Rating Scale (SHRS) is concluded that the SHRS represents an easily completed, reliable, valid and sensitive rating scale for extrapyramidal symptoms that can be used with and without videotapes and divergent validity between all of the other scales.
Journal ArticleDOI
Atypical antipsychotics for disruptive behaviour disorders in children and youths
TL;DR: The aim was to evaluate each drug separately rather than the class effect, on the grounds that each atypical antipsychotic has different pharmacologic binding profile and that this is clinically more useful.
Journal ArticleDOI
Amisulpride, an atypical antipsychotic, in the treatment of acute episodes of schizophrenia: a dose-ranging study vs. haloperidol
A.J. Puech,O. Fleurot,W. Rein +2 more
TL;DR: It is concluded that amisulpride 400 mg and 800 mg/day is highly effective in treating the positive symptoms of schizophrenia, with less extrapyramidal side‐effects than haloperidol 16 mg/ day.
Journal ArticleDOI
Aripiprazole once-monthly for treatment of schizophrenia: double-blind, randomised, non-inferiority study
W. Wolfgang Fleischhacker,Raymond Sanchez,Pamela Perry,Na Jin,Timothy Peters-Strickland,B. Johnson,Ross A. Baker,Anna Eramo,Robert D. McQuade,William H. Carson,David P. Walling,John M. Kane +11 more
TL;DR: Aripiprazole once-monthly 400mg was non-inferior to oral aripipazole, and the reduction in Kaplan–Meier estimated impending relapse rate at week 26 was statistically significant.
Journal ArticleDOI
Idazoxan and response to typical neuroleptics in treatment-resistant schizophrenia. Comparison with the atypical neuroleptic, clozapine.
TL;DR: The addition of idazoxan to fluphenazine treatment resulted in significant reductions of global psychosis and total, positive and negative symptoms on the Brief Psychiatric Rating Scale, compared to neuroleptic treatment alone.
References
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Journal Article
Relationship of individual tolerance, behavior and phenothiazine produced extrapyramidal system disturbance.
Simpson Gm,Kunz-Bartholini E +1 more
Journal Article
Pharmacologically induced Parkinson-like signs as index of the therapeutic potential.
Journal ArticleDOI
The Action of Neuroleptic Drugs.
TL;DR: The major portion of this monograph consists of a restatement by the senior author of his concepts regarding the modus operandi and therapeutic use of the neuroleptic drugs in clinical psychiatry.