Journal ArticleDOI
A rating scale for extrapyramidal side effects
Reads0
Chats0
TLDR
A modification of an earlier rating scale for extrapyramidal system disturbance is described, and evidence for the validity and reliability of the scale is presented.Abstract:
SUMMARY
A modification of an earlier rating scale for extrapyramidal system disturbance is described, and evidence for the validity and reliability of the scale is presented. The usefulness of the scale in studies of neuroleptic drugs is discussed. By its application it is possible to quantify extrapyramidal side effects and to separate them into four principal factors.read more
Citations
More filters
Journal ArticleDOI
The efficacy and safety of aripiprazole as adjunctive therapy in major depressive disorder: a second multicenter, randomized, double-blind, placebo-controlled study.
Ronald N. Marcus,Robert D. McQuade,William H. Carson,Delphine Hennicken,Maurizio Fava,Jeffrey S. Simon,Madhukar H. Trivedi,Michael E. Thase,Robert M. Berman +8 more
TL;DR: Aripiprazole is an effective and safe adjunctive therapy as demonstrated in this short-term study for patients who are nonresponsive to standard ADT.
Journal ArticleDOI
Manual for the Extrapyramidal Symptom Rating Scale (ESRS).
TL;DR: ESRS specificity was investigated through two different approaches, path analyses and ANCOVA PANSS factors changes, which found that ESRS measurement of drug-induced EPS is valid and discriminative from psychiatric symptoms.
Journal ArticleDOI
Efficacy of olanzapine in combination with valproate or lithium in the treatment of mania in patients partially nonresponsive to valproate or lithium monotherapy.
Mauricio Tohen,Mauricio Tohen,K. N. Roy Chengappa,Trisha Suppes,Carlos A. Zarate,Joseph R. Calabrese,Charles L. Bowden,Gary S. Sachs,David J. Kupfer,Robert W. Baker,Richard C. Risser,Elisabeth L. Keeter,Peter D. Feldman,Gary D. Tollefson,Alan Breier +14 more
TL;DR: Compared with the use of valproate or lithium alone, the addition of olanzapine provided superior efficacy in the treatment of manic and mixed bipolar episodes.
Journal ArticleDOI
Randomized Controlled Trial of Effect of Prescription of Clozapine Versus Other Second-Generation Antipsychotic Drugs in Resistant Schizophrenia
Shôn Lewis,Thomas R. E. Barnes,Linda Davies,Robin M. Murray,Graham Dunn,Karen P. Hayhurst,A. Markwick,Helen Lloyd,Peter B. Jones +8 more
TL;DR: In people with schizophrenia with poor treatment response to 2 or more antipsychotic drugs, there is an advantage to commencing clozapine rather than other SGA drugs in terms of symptom improvement over 1 year.
Journal ArticleDOI
Olanzapine versus placebo: results of a double-blind, fixed-dose olanzapine trial.
Charles M. Beasley,Todd M. Sanger,Winston Satterlee,Gary D. Tollefson,Pierre V. Tran,Susan H. Hamilton +5 more
TL;DR: Olanzapine appears to be not only safe and effective, but a promising atypical antipsychotic candidate.
References
More filters
Journal Article
Relationship of individual tolerance, behavior and phenothiazine produced extrapyramidal system disturbance.
Simpson Gm,Kunz-Bartholini E +1 more
Journal Article
Pharmacologically induced Parkinson-like signs as index of the therapeutic potential.
Journal ArticleDOI
The Action of Neuroleptic Drugs.
TL;DR: The major portion of this monograph consists of a restatement by the senior author of his concepts regarding the modus operandi and therapeutic use of the neuroleptic drugs in clinical psychiatry.