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A Review on Green Synthesis of Zinc Oxide Nanoparticles Using Plant Extracts and Its Biomedical Applications

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TLDR
A review of the recent advances in the synthesis, mechanism routes, characterization techniques, and applications of biosynthesized ZnO NPS in agriculture, medicine, and textile industries is presented in this paper.
Abstract
Zinc oxide nanoparticles (ZnO NPs) are one of the prominent metal oxide nanoparticles with significant applications in many industries and research institutes. Various methods of synthesis have been adopted in the production of ZnO NPs so as to meet its high demand. The environmental implications and economic challenges attached to most of the means of ZnO NPs synthesis have resulted in the quest for other alternatives with environmental and economic benefits. Interestingly, the biological method of synthesis using plant sources have been found appropriate for the production of ZnO NPs dues to its numerous health, environmental, economic, and medicinal benefits. The distinctive features of ZnO NPs synthesized using plant extracts enhanced its application in agriculture for the production of fertilizers, pesticides, and fumigants. In the field of medicine and pharmacy, phytosynthesized ZnO NPs have gained remarkable usage in the production of disinfectant, antifungal, anticancer, antioxidant, anti-inflammatory and antidiabetics agents. Despite the enlisted benefits of biosynthesized ZnO NPs, the difficulties associated with the elucidation of formation mechanism and reactions still remain unraveled. This review described the summary of the recent advances in the synthesis, mechanism routes, characterization techniques, and applications of biosynthesized ZnO NPS in agriculture, medicine, and textile industries.

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Recent Advances in Zinc Oxide Nanoparticles (ZnO NPs) for Cancer Diagnosis, Target Drug Delivery, and Treatment.

TL;DR: In this article, the role of zinc oxide nanoparticles (ZnO NPs) in diagnosis and bio-imaging of cancer cells is discussed, with a special focus on surface functionalization, drugloading mechanism, and stimuli-responsive controlled release of drugs.
Journal ArticleDOI

Exploring the Journey of Zinc Oxide Nanoparticles (ZnO-NPs) toward Biomedical Applications

TL;DR: In this article , the potential biomedical applications of green synthesized zinc oxide nanoparticles (ZnO-NPs) have been investigated, which shows that they have outstanding potential as a potent biological agent, as well as related hazardous properties.
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A state of the art review on the synthesis, antibacterial, antioxidant, antidiabetic and tissue regeneration activities of zinc oxide nanoparticles.

TL;DR: Zinc oxide nanoparticles (ZnONPs) have gained much interest of nanobiotechnologists due to their profound biomedical applications as discussed by the authors, which can cause both gram-positive and negative bacterial cell death through the generation of reactive free radicals as well as membrane rupture.
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Structural Properties and Antimicrobial Activities of Polyalthia longifolia Leaf Extract-Mediated CuO Nanoparticles

TL;DR: The results indicated that the proactive eco-benign fabrication of CuONPs by sustainable “green chemistry” approaches can offer a convenient alternative to orthodox multi-step strategies for the creation ofCuONPs.
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Green synthesis of ZrO2 nanoparticles and nanocomposites for biomedical and environmental applications: a review

TL;DR: A review of the synthesis of ZrO2 nanoparticles and their nanocomposites using compounds from bacteria, fungi, microalgae, and plants can be found in this article .
References
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Journal ArticleDOI

Review on Zinc Oxide Nanoparticles: Antibacterial Activity and Toxicity Mechanism.

TL;DR: This review covered ZnO-NPs antibacterial activity including testing methods, impact of UV illumination,ZnO particle properties (size, concentration, morphology, and defects), particle surface modification, and minimum inhibitory concentration.
Journal ArticleDOI

The antimicrobial activity of nanoparticles: present situation and prospects for the future

TL;DR: The antibacterial mechanisms of NPs against bacteria and the factors that are involved are discussed and the limitations of current research are discussed.
Journal ArticleDOI

Silver Nanoparticles: Synthesis, Characterization, Properties, Applications, and Therapeutic Approaches

TL;DR: This review extensively discusses the multifunctional bio-applications of AgNPs; for example, as antibacterial, antifungal, antiviral,Anti-inflammatory, anti-angiogenic, and anti-cancer agents, and the mechanism of the anti- cancer activity of Ag NPs.
Journal ArticleDOI

Phytochemicals: Extraction, Isolation, and Identification of Bioactive Compounds from Plant Extracts

TL;DR: There are concerns about using synthetic phenolic antioxidants as food additives because of the reported negative effects on human health, so a replacement of these synthetics by antioxidant extractions from various foods has been proposed.
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