Journal ArticleDOI
A single-ring OpenPET enabling PET imaging during radiotherapy
Hideaki Tashima,Taiga Yamaya,Eiji Yoshida,Shoko Kinouchi,Shoko Kinouchi,Mitsuo Watanabe,Eiichi Tanaka +6 more
TLDR
A second-generation OpenPET geometry, single-ring OpenPET, is proposed, which can provide an accessible and observable open space with higher sensitivity and a reduced number of detectors than the earlier one and results indicate that the depth-of-interaction detector can provide uniform resolution even when the detectors are arranged in an ellipsoidal ring.Abstract:
We develop an OpenPET system which can provide an accessible open space to the patient during PET scanning. Our first-generation OpenPET geometry which we called dual-ring OpenPET consisted of two separated detector rings and it could extend its axial field of view (FOV) therefore enabling imaging the gap region in addition to the in-ring region. However, applications such as dose verification by in-beam PET measurement during particle therapy and real-time tumor tracking by PET require sensitivity focused onto the gap rather than on the wide FOV. In this paper, we propose a second-generation OpenPET geometry, single-ring OpenPET, which can provide an accessible and observable open space with higher sensitivity and a reduced number of detectors than the earlier one. The proposed geometry has a cylinder shape cut at a slant angle, in which the shape of each cut end becomes an ellipse. We provided a theoretical analysis for sensitivity of the proposed geometry, compared with the dual-ring OpenPET and a geometry where the conventional PET was positioned at a slant angle against the patient bed to form an accessible open space, which we called a slant PET. The central sensitivity depends on the solid angle of these geometries. As a result, we found that the single-ring OpenPET has a sensitivity 1.2 times higher than the dual-ring OpenPET and 1.3 times higher than the slant PET when designed for a 600 mm bed width with 300 mm accessible open space and about 200 detector blocks, each with a front area of 2500 mm². In addition, numerical simulation was carried out to show the imaging property of the proposed geometry realized with the ellipsoidal rings and these results indicate that the depth-of-interaction detector can provide uniform resolution even when the detectors are arranged in an ellipsoidal ring.read more
Citations
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Journal ArticleDOI
Recent developments in time-of-flight PET
TL;DR: Recent developments in system design, image reconstruction, corrections, and the potential in new applications for TOF-PET are reviewed to introduce the reader in an educational way into the topic of time-of-flight-PET.
Journal ArticleDOI
Nuclear physics in particle therapy: a review.
Marco Durante,Harald Paganetti +1 more
TL;DR: Research in applied nuclear physics, including nuclear interactions, dosimetry, image guidance, range verification, novel accelerators and beam delivery technologies, can significantly improve the clinical outcome in particle therapy.
Journal ArticleDOI
Prompt-gamma monitoring in hadrontherapy: A review
TL;DR: In this paper, a review and discussion of the state of the art for all techniques using prompt-gamma detection to improve the quality assurance in hadrontherapy is presented.
Journal ArticleDOI
In vivo range verification in particle therapy.
Katia Parodi,Jerimy C. Polf +1 more
TL;DR: This contribution critically reviews methods under development or clinical testing for verification of ion therapy, based on pretreatment range and tissue probing as well as the detection of secondary emissions or physiological changes during and after treatment, to disentangle approaches of general applicability from those more specific to certain anatomical locations.
Journal ArticleDOI
Range Verification Methods in Particle Therapy: Underlying Physics and Monte Carlo Modeling
TL;DR: A comprehensive overview of various aspects in modeling the physics processes for range verification with secondary particles produced in proton, carbon, and heavier ion irradiation, and some widely used MC codes in hadron therapy are described.
References
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A review of partial volume correction techniques for emission tomography and their applications in neurology, cardiology and oncology
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Journal Article
Performance of Philips Gemini TF PET/CT Scanner with Special Consideration for Its Time-of-Flight Imaging Capabilities
Suleman Surti,Austin Kuhn,Matthew E. Werner,Amy E. Perkins,Jeffrey A. Kolthammer,Joel S. Karp +5 more
TL;DR: The Gemini TF whole-body scanner represents the first commercially available fully 3-dimensional PET scanner that achieves time-of-flight capability as well as conventional imaging capabilities.