Journal ArticleDOI
ALK-1-negative anaplastic large cell lymphoma associated with breast implants: a new clinical entity.
Davide Lazzeri,Tommaso Agostini,Guido Bocci,Giordano Giannotti,Giovanni Fanelli,Antonio Giuseppe Naccarato,Romano Danesi,Marco Tuccori,Marcello Pantaloni,Carlo D'Aniello +9 more
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TLDR
Clinical and pathologic findings are reviewed to show convincing evidence that primary implant-related ALK-1(-) ALCL represents a distinct clinicopathologic entity that has been inappropriately fitted into the category of systemic ALK(-) AlCL and should be recognized as a separate category and classified on its own.About:
This article is published in Clinical Breast Cancer.The article was published on 2011-10-01. It has received 75 citations till now. The article focuses on the topics: Anaplastic large-cell lymphoma & Breast implant.read more
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Journal ArticleDOI
A paradigm shift in U.S. Breast reconstruction: increasing implant rates.
Claudia R. Albornoz,Peter B. Bach,Babak J. Mehrara,Joseph J. Disa,Andrea L. Pusic,Colleen M. McCarthy,Peter G. Cordeiro,Evan Matros +7 more
TL;DR: Although the reason for the increase in implant use is multifactorial, changes in mastectomy patterns, such as increased use of bilateral mastectomies, are one important contributor.
Journal ArticleDOI
Breast Implant-Associated Anaplastic Large Cell Lymphoma: A Systematic Review.
Ashley N. Leberfinger,Brittany J. Behar,Nicole Williams,Kevin Rakszawski,John Potochny,Donald R. Mackay,Dino J. Ravnic +6 more
TL;DR: Assessment of how BIA-ALCL develops, its risk factors, diagnosis, and subsequent treatment and to disseminate information about this entity to the medical field is conducted.
Journal ArticleDOI
Silicone implants and lymphoma: The role of inflammation.
Mojca Bizjak,Carlo Selmi,Sonja Praprotnik,Or Bruck,Carlo Perricone,Michael Ehrenfeld,Yehuda Shoenfeld +6 more
TL;DR: It is suggested that polyclonal activation may result in monoclonality in those at risk hosts, ultimately leading to lymphoma, and that patients with an inflammatory response against silicone implants be monitored carefully.
Journal ArticleDOI
Survival Signals and Targets for Therapy in Breast Implant–Associated ALK− Anaplastic Large Cell Lymphoma
Melissa G. Lechner,Carolina Megiel,Connor H. Church,Trevor E. Angell,Sarah M. Russell,Rikki B. Sevell,Julie K. Jang,Garry S. Brody,Alan L. Epstein +8 more
TL;DR: The TLBR cell lines closely resemble the primary breast implant–associated lymphomas from which they were derived and as such provide valuable preclinical models to study their unique biology.
Journal ArticleDOI
Breast implant-associated anaplastic large cell lymphoma: a review.
Andrés E. Quesada,L. Jeffrey Medeiros,Mark W. Clemens,Maria C. Ferrufino-Schmidt,Sergio Pina-Oviedo,Roberto N. Miranda +5 more
TL;DR: A comprehensive review of breast implant-associated anaplastic large cell lymphoma, including history, epidemiology, clinical features, imaging and pathology findings, pathologic handling, pathogenic mechanisms, model for progression, therapy and outcomes as well as an analysis of causality between breast implants and anaplastics large cellymphoma are provided.
References
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Journal ArticleDOI
The expression of the Hodgkin's disease associated antigen Ki-1 in reactive and neoplastic lymphoid tissue: evidence that Reed-Sternberg cells and histiocytic malignancies are derived from activated lymphoid cells.
Harald Stein,D Y Mason,Johannes Gerdes,N O'Connor,J. S. Wainscoat,Gorm Pallesen,K C Gatter,B Falini,Georges Delsol,Hilmar Lemke,R Schwarting,Karl Lennert +11 more
TL;DR: Results obtained indicate that Ki-1 antigen is an inducible lymphoid-associated molecule that identifies a group of hitherto poorly characterized normal and neoplastic large lymphoid cells in Hodgkin's disease and Disorders in which only a minority of cells express Ki- 1 antigen probably represent lesions in whichonly some of the abnormal cells have transformed into an "activation state.
Journal ArticleDOI
Prognostic significance of anaplastic lymphoma kinase (ALK) protein expression in adults with anaplastic large cell lymphoma
Randy D. Gascoyne,Patricia Aoun,Patricia Aoun,Patricia Aoun,Daniel Wu,Daniel Wu,Daniel Wu,Mukesh Chhanabhai,Mukesh Chhanabhai,Mukesh Chhanabhai,Brian F. Skinnider,Brian F. Skinnider,Brian F. Skinnider,Timothy C. Greiner,Timothy C. Greiner,Timothy C. Greiner,Stephan W. Morris,Stephan W. Morris,Stephan W. Morris,Joseph M. Connors,Joseph M. Connors,Joseph M. Connors,Julie M. Vose,Julie M. Vose,Julie M. Vose,David S. Viswanatha,David S. Viswanatha,David S. Viswanatha,Andrew Coldman,Andrew Coldman,Andrew Coldman,Dennis D. Weisenburger,Dennis D. Weisenburger,Dennis D. Weisenburger +33 more
TL;DR: It is concluded that ALCL is a heterogeneous disorder, however, ALK protein expression is an independent predictor of survival and serves as a useful biologic marker of a specific disease entity within the spectrum of ALCL.
Journal ArticleDOI
Anaplastic T-cell lymphoma in proximity to a saline-filled breast implant.
John A. Keech,Brevator J. Creech +1 more
Journal ArticleDOI
Complications Leading to Surgery after Breast Implantation
Sherine E. Gabriel,John E. Woods,W. Michael O'Fallon,C. Mary Beard,Leonard T. Kurland,L. Joseph Melton +5 more
TL;DR: Women who have had breast implantation frequently experience local complications during the subsequent five years, and complications were significantly less frequent among patients who received implants for cosmetic reasons than among those whoreceived implants after mastectomy for cancer or for cancer prophylaxis.
Journal ArticleDOI
Meta-analyses of the relation between silicone breast implants and the risk of connective-tissue diseases.
TL;DR: From a public health perspective, breast implants appear to have a minimal effect on the number of women in whom connective-tissue diseases develop, and the elimination of implants would not be likely to reduce the incidence of connectives-Tissue diseases.
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