Altered Affective Response in Marijuana Smokers: An FMRI Study
TLDR
Differences in affective processing in chronic smokers are suggested, even when stimuli are presented below the level of conscious processing, and underscore the likelihood that marijuana smokers process emotional information differently from those who do not smoke, which may result in negative consequences.About:
This article is published in Drug and Alcohol Dependence.The article was published on 2009-11-01 and is currently open access. It has received 160 citations till now.read more
Citations
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Dysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications
TL;DR: Functional neuroimaging studies conducted in the past decade that have expanded the understanding of the involvement of the PFC in drug addiction are focused on.
Antidepressant-Like Activity and Modulation of Brain Monoaminergic Transmission by Blockade of Anandamide Hydrolysis
Gabriella Gobbi,Francis Rodriguez Bambico,Regina A. Mangieri,Marco Bortolato,Patrizia Campolongo,Tommaso Cassano,Maria Grazia Morgese,Guy Debonnel,Andrea Duranti,A. Tontini,Giorgio Tarzia,Marco Mor,Viviana Trezza,Steven R. Goldberg,Vincenzo Cuomo,Daniele Piomelli +15 more
TL;DR: Gobi et al. as discussed by the authors showed that URB597, a selective inhibitor of the enzyme fatty acid amide hydrolase, which catalyzes the intracellular hydrolysis of the endocannabinoid anandamide, exerts potent antidepressant-like effects in the mouse tail-suspension test and the rat forced-swim test.
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Structural and Functional Imaging Studies in Chronic Cannabis Users: A Systematic Review of Adolescent and Adult Findings
Albert Batalla,Sagnik Bhattacharyya,Murat Yücel,Paolo Fusar-Poli,José Alexandre de Souza Crippa,José Alexandre de Souza Crippa,Santiago Nogué,Marta Torrens,Jesús Pujol,Magí Farré,Rocío Martín-Santos,Rocío Martín-Santos +11 more
TL;DR: Chronic cannabis use may alter brain structure and function in adult and adolescent population and functional neuroimaging studies suggest different patterns of resting global and brain activity during the performance of several cognitive tasks both in adolescents and adults may indicate compensatory effects in response to chronic cannabis exposure.
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Age of onset of marijuana use and executive function.
TL;DR: Findings suggest that earlier MJ onset is related to poorer cognitive function and increased frequency and magnitude of MJ use relative to later MJ onset, and exposure to MJ during a period of neurodevelopmental vulnerability, such as adolescence, may result in altered brain development and enduring neuropsychological changes.
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Modulation of risk-taking in marijuana users by transcranial direct current stimulation (tDCS) of the dorsolateral prefrontal cortex (DLPFC)
Paulo S. Boggio,Soroush Zaghi,Ana Beatriz Villani,Shirley Fecteau,Alvaro Pascual-Leone,Felipe Fregni,Felipe Fregni +6 more
TL;DR: It is observed that right anodal/left cathodal tDCS of DLPFC is significantly associated with a diminished craving for marijuana and alterations in the decision-making neural networks among chronic marijuana users are revealed.
References
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