Journal ArticleDOI
An update on lignans: natural products and synthesis.
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TLDR
This review covers the source, chemistry and bioactivities of natural lignans, and highlights the total syntheses of some lignan motifs and asymmetric synthese of their motifs.About:
This article is published in Natural Product Reports.The article was published on 2009-09-23. It has received 201 citations till now.read more
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Natural Products Version 2.0: Connecting Genes to Molecules
TL;DR: This Perspective explores how connecting Nature's small molecules to the genes that encode them has sparked a renaissance in natural product research, focusing primarily on the biosynthesis of polyketides and non-ribosomal peptides.
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Recent advances in research on lignans and neolignans
TL;DR: This review describes 564 of the latest examples of naturally occurring lignans and neolignans, and their glycosides in some cases, which have been isolated between 2009 and 2015 and highlights the biosynthesis and total synthesis of some important ones.
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Supramolecular self-assembled chaos: polyphenolic lignin's barrier to cost-effective lignocellulosic biofuels
Komandoor Elayavalli Achyuthan,Ann Mary Achyuthan,Paul D. Adams,Shawn Matthew Dirk,Jason C. Harper,Blake A. Simmons,Anup K. Singh +6 more
TL;DR: Supramolecular self-assembly, nano-mechanical properties of lignin-lignin, lign in-polysaccharide interactions and association-dissociation kinetics affect biomass deconstruction and thereby cost-effective biofuels production.
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Naturally lignan-rich foods: a dietary tool for health promotion?
Carmen Rodríguez-García,Cristina Sánchez-Quesada,Estefanía Toledo,Miguel Delgado-Rodríguez,Miguel Delgado-Rodríguez,José J. Gaforio +5 more
TL;DR: Dietary intake of lignan-rich foods could be a useful way to bolster the prevention of chronic illness, such as certain types of cancers and cardiovascular disease, according to the latest humans’ findings.
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Recent developments in qualitative and quantitative analysis of phytochemical constituents and their metabolites using liquid chromatography-mass spectrometry.
TL;DR: This paper mainly focuses on screening and characterization of phenols (including flavonoids), alkaloids, terpenoids, steroids, coumarins, lignans, and miscellaneous compounds in respective herbs and biological samples, as well as traditional Chinese medicine prescriptions using tandem mass spectrometer.
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Antioxidant activity of the flaxseed lignan secoisolariciresinol diglycoside and its mammalian lignan metabolites enterodiol and enterolactone.
TL;DR: The efficacy of SDG and particularly the mammalian lignans ED and EL to act as antioxidants in lipid and aqueous in vitro model systems, at relatively low concentrations (i.e. 100 μM), potentially achievable in vivo, is an evidence of a potential anticarcinogenic mechanism.
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An update on bioactive plant lignans
TL;DR: This review deals with lignan possessing anticancer, antioxidant, antimicrobial, anti-inflammatory and immunosuppressive activities, and comprises the data reported in more than 100 peer-reviewed articles so as to highlight the recently reported bioactive lignans that could be a first step towards the development of potential new therapeutic agents.
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Natural flavonoids and lignans are potent cytostatic agents against human leukemic HL-60 cells
TL;DR: Results showed that some of the naturally occurring flavonoids and lignans inhibited HL-60 cell growth with a non-toxic mechanism, possibly via cessation of DNA, RNA, and/or protein synthesis of the leukemic cells.
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Antitumorigenic effect of a mammalian lignan precursor from flaxseed
TL;DR: It is shown, for the first time, that SD has an antitumor effect when provided at the early promotion stage of tumorigenesis and may contribute to the health benefits of high-fiber foods.
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Antioxidant activity and bioactive compounds of tea seed (Camellia oleifera Abel.) oil.
Chia-Pu Lee,Gow-Chin Yen +1 more
TL;DR: The results indicate that both compounds isolated from tea seed oil exhibit remarkable antioxidant activity.