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Open AccessJournal ArticleDOI

Annual Plasmodium falciparum entomological inoculation rates (EIR) across Africa: literature survey, Internet access and review.

TLDR
An extensive search of the formal and informal literature on annual Plasmodium falciparum entomological inoculation rates across Africa from 1980 onwards supports the idea of highly heterogeneous risk at the continental, regional and country levels.
Abstract
This paper presents the results of an extensive search of the formal and informal literature on annual Plasmodium falciparum entomological inoculation rates (EIR) across Africa from 1980 onwards. It first describes how the annual EIR data were collated, summarized, geo-referenced and staged for public access on the internet. Problems of data standardization, reporting accuracy and the subsequent publishing of information on the internet follow. The review was conducted primarily to investigate the spatial heterogeneity of malaria exposure in Africa and supports the idea of highly heterogeneous risk at the continental, regional and country levels. The implications for malaria control of the significant spatial (and seasonal) variation in exposure to infected mosquito bites are discussed.

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A world malaria map: Plasmodium falciparum endemicity in 2007

TL;DR: This 2007 global P. falciparum malaria endemicity map is the first of a series with which it will be possible to monitor and evaluate the progress of this intervention process, and shows significant opportunities for malaria control in Africa and for malaria elimination elsewhere.
Journal ArticleDOI

The global distribution and population at risk of malaria: past, present, and future

TL;DR: This paper used geographic information systems in combination with historical maps to quantify the anthropogenic impact on the distribution of malaria in the 20th century, finding that despite human activities reducing by half the land area supporting malaria, demographic changes resulted in a 2 billion increase in the total population exposed to malaria risk.
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Evolutionary and Historical Aspects of the Burden of Malaria

TL;DR: Only by following, or attempting to follow, malaria throughout its evolution and history can the authors understand its character and so be better prepared for the future management of this ancient ill.
References
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Journal ArticleDOI

A Climate-based Distribution Model of Malaria Transmission in Sub-Saharan Africa

TL;DR: A simple numerical approach to defining distribution of malaria transmission, based upon biological constraints of climate on parasite and vector development, provides a numerical basis for further refinement and prediction of the impact of climate change on transmission.
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Relation between severe malaria morbidity in children and level of Plasmodium falciparum transmission in Africa

TL;DR: It is proposed that a critical determinant of life-time disease risk is the ability to develop clinical immunity early in life during a period when other protective mechanisms may operate, and measures which reduce parasite transmission, and thus immunity, may lead to a change in both the clinical spectrum of severe disease and the overall burden of severe malaria morbidity.

Estimating mortality, morbidity and disability due to malaria among Africa's non-pregnant

TL;DR: This work has taken an empirical approach to defining the limits of Plasmodium falciparum transmission across the continent and interpolated the distributions of projected populations in 1995 by combining a review of the literature on malaria in Africa and models of acquired functional immunity.
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The Cochrane Collaboration: Preparing, Maintaining, and Disseminating Systematic Reviews of the Effects of Health Care

TL;DR: The Cochrane Collaboration has evolved in response to this challenge and will eventually cover all areas of health care and contributors in many countries and specialties are preparing and maintaining systematic reviews of RCTs, and reviews of other evidence when appropriate.
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