Journal ArticleDOI
Antibacterial activity of plants used in Indian herbal medicine
TLDR
Potential use of these plants for developing new antibacterial compounds against pathogenic microorganisms is revealed and the presence of phytochemicals such as alkaloids, tannins, triterpenoids, steroids and glycosides in the extracts ofThese plants supports their traditional uses as medicinal plants for the treatment of various ailments.Abstract:
Delonix elata, Enicostemma axillare, Merremia tridentata, Mollugo cerviana and Solanum incanum are medicinal plants used in traditional Indian medicine for the treatment of various ailments. These plants were selected to evaluate their potential antibacterial activity. To determine antibacterial activity and phytochemicals in the crude extracts of five medicinal plants used in traditional Indian medicine for the treatment of various ailments like rheumatism, piles fever, skin diseases and snake bite. The antibacterial activity of organic solvent extracts of these plants were determined by disc diffusion and broth dilution techniques against grampositive bacterial strains (Bacillus subtilis, Staphylococcus aureus) and gram-negative bacterial strains (Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa). Results revealed that the chloroform and methanol extracts of D. elata and methanol extracts of M. cerviana exhibited significant antibacterial activity against gram-positive and gram-negative strains with minimum bactericidal concentration (MBC) ranging from 1.5 to 100 mg/ml. Methanol extracts of M. tridentata exhibited activity only against gram-positive bacterial strains with MBC ranging from 12.5 to 100 mg/ml. Extracts of E. axillare and S. incanum showed activity only against B. subtilis and were not bactericidal at 100 mg/ml. The most susceptible organism to the organic extracts from all the studied plants was B. subtilis and the most resistant organism was P. aeruginosa. The presence of phytochemicals such as alkaloids, tannins, triterpenoids, steroids and glycosides in the extracts of these plants supports their traditional uses as medicinal plants for the treatment of various ailments. The present study reveals potential use of these plants for developing new antibacterial compounds against pathogenic microorganisms. Key words: Antibacterial, Enicostemma axillare, Merremia tridentata, Mollugo cerviana, Solanum incanumread more
Citations
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Journal ArticleDOI
Do herbal medicines have potential for managing snake bite envenomation
Y K Gupta,S S Peshin +1 more
TL;DR: The present article reviews the current status of various medicinal plants for the management of snake bite and concludes that numerous unexplored plants claimed to be antidotes in folklore medicine need to be studied.
Studies on Anti-oxidant activity of Tinospora cordifolia (Miers.) Leaves using in vitro models
Ramya Premanath,N. Lakshmidevi +1 more
TL;DR: In this article, the anti-oxidant effects of leaves of Tinospora cordifolia were examined by using different in vitro models such as total reducing power, total antioxidant activity, lipid peroxidation inhibitory activity, DPPH radical scavenging activity and superoxide radical scavengence activity.
Medicinal flora of the cholistan desert: a review
Mansoor Hameed,Muhammad Ashraf,F. Al-Quriany,Tahira Nawaz,Muhammad Sajid,Aqeel Ahmad,Adnan Younis,Nargis Naz +7 more
TL;DR: The Cholistan desert is characterized by large saline compacted areas with alluvial clay, sandy ridges and dunes, and semi-stabilized to frequently shifting dunes as mentioned in this paper.
Journal ArticleDOI
Antimicrobial and antioxidant properties of methanol extract, fractions and compounds from the stem bark of Entada abyssinica Stend ex A. Satabie
Gerald Ngo Teke,Paul Keilah Lunga,Hippolyte K. Wabo,Jules-Roger Kuiate,Gérard Vilarem,Géraldine Giacinti,Haruhisa Kikuchi,Yoshiteru Oshima +7 more
TL;DR: The results obtained from this study support the ethnomedicinal use of E. abyssinica in the treatment of gastrointestinal infections and the isolated compounds could be useful in the standardisation of antimicrobial phytomedicine from this plant.
Journal ArticleDOI
Snake Bite in India: Current Scenario of an Old Problem
TL;DR: An assortment of herbal plants used in India for snake bites is highlighted, as herbals are cheap, acceptable and often at the disposal of victims.
References
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Journal ArticleDOI
The anti-inflammatory activity of Enicostemma littorale and Mollugo cerviana.
TL;DR: These drugs were found to inhibit the levels of lipid peroxides, acid phosphatase, and gamma-glutamyl transpeptidase activity in the exudate of cotton pellet granuloma and were compared with those of standard anti-inflammatory drug, hydrocortisone.
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Natural Triterpenoids as Anti-Inflammatory Agents
TL;DR: This chapter reviews the natural triterpenes with anti-inflammatory activity, including the traditional ones and the new compounds isolated over the last six years.
Antimicrobial effects of components of the bark extract of neem(Azadirachta indica A. J uss)
TL;DR: In this article, the antimicrobial spectrum of the aqueous, methanol and acetone extracts of A. indica was determined by agar diffusion method, and it was concluded that there is a scientific basis for traditional use of extracts of bark and leaves.
Journal Article
Antibacterial activity of black myrobalan (fruit of terminalia chebula Retz.) against uropathogen Escherichia coli
Rabi Ranjan Chattopadhyay,Subir Kumar Bhattacharyya,C. Medda,Sunanda Chanda,S Datta,N. K. Pal +5 more
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Pharmacodynamics and drug development : perspectives in clinical pharmacology
TL;DR: Partial table of contents: OVERVIEW of PHARMACODYNAMICS.