Journal ArticleDOI
Antibacterial adhesive injectable hydrogels with rapid self-healing, extensibility and compressibility as wound dressing for joints skin wound healing.
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TLDR
In vivo experiments indicated that curcumin loaded hydrogels significantly accelerated wound healing rate with higher granulation tissue thickness and collagen disposition and upregulated vascular endothelial growth factor (VEGF) in a full-thickness skin defect model.About:
This article is published in Biomaterials.The article was published on 2018-11-01. It has received 1102 citations till now. The article focuses on the topics: Self-healing hydrogels & Granulation tissue.read more
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A highly-stretchable and adhesive hydrogel for noninvasive joint wound closure driven by hydrogen bonds
Hongshen Liu,Xiaole Hu,Wen Li,Meiling Zhu,Jinhuan Tian,Lihua Li,Binghong Luo,Changren Zhou,Lu Lu +8 more
TL;DR: In this article , a highly stretchable, adhesive, transparent and hygroscopic hydrogel for non-invasive joint wound closure is reported, which is composed of N-[Tris (hydroxymethyl) methyl] acrylamide (THMA), polyethylene glycol diacrylate (PEGDA) and sodium alginate (SA).
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An injectable hydrogel dotted with dexamethasone acetate-encapsulated reactive oxygen species-scavenging micelles for combinatorial therapy of osteoarthritis
A. Wach,Brandon Goodwin +1 more
TL;DR: In this article , a ROS-scavenging and drug-release platform was prepared via encapsulating dexamethasone acetate (DA)-loaded reactive oxygen species (ROS) into an injectable hydrogel.
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Benlysta-Loaded Sodium Alginate Hydrogel and Its Selective Functions in Promoting Skin Cell Growth and Inhibiting Inflammation.
TL;DR: Live/dead staining images and the CCK-8 results showed that the benlysta-loaded hydrogel could promote the growth of human epidermal cells, fibroblasts, and endothelial cells while inhibiting the aggregation of inflammatory cells (macrophages).
Journal ArticleDOI
Current Advances in the Development of Hydrogel-Based Wound Dressings for Diabetic Foot Ulcer Treatment
V Güiza-Argüello,Víctor Alfonso Solarte-David,A. V. Pinzon-Mora,J.E. Ávila-Quiroga,Silvia Becerra-Bayona +4 more
TL;DR: This review paper addresses the most recent advances in hydrogel wound dressings for effective DFU treatment, providing an overview of current perspectives and challenges in this research field.
Journal ArticleDOI
An injectable hydrogel dotted with dexamethasone acetate-encapsulated ROS-scavenging micelles for combinatorial therapy of osteoarthritis
A. Wach,Tong Zhou,Brandon Goodwin,Hao Xiong,Shuqin Wang,Hao Lan Zhang,Weiwei Zheng,Zhongru Gou,Cunyi Fan,Changyou Gao +9 more
TL;DR: In this paper, a ROS-scavenging and drug-release platform was prepared via encapsulating dexamethasone acetate (DA)-loaded reactive oxygen species (ROS) into an injectable hydrogel.
References
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Journal ArticleDOI
Cutaneous wound healing.
TL;DR: The primary goals of the treatment of wounds are rapid wound closure and a functional and aesthetically satisfactory scar.
Journal ArticleDOI
Highly stretchable and tough hydrogels
Jeong-Yun Sun,Xuanhe Zhao,Widusha R. K. Illeperuma,Ovijit Chaudhuri,Kyu Hwan Oh,David J. Mooney,David J. Mooney,Joost J. Vlassak,Zhigang Suo +8 more
TL;DR: The synthesis of hydrogels from polymers forming ionically and covalently crosslinked networks is reported, finding that these gels’ toughness is attributed to the synergy of two mechanisms: crack bridging by the network of covalent crosslinks, and hysteresis by unzipping thenetwork of ionic crosslinks.
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Multiple biological activities of curcumin: a short review.
TL;DR: This review summarizes the most interesting in vitro and in vivo studies on the biological effects of curcumin, the constituent of turmeric, which has been widely studied for its anti-inflammatory, anti-angiogenic,Anti-oxidant, wound healing and anti-cancer effects.
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Antibacterial anti-oxidant electroactive injectable hydrogel as self-healing wound dressing with hemostasis and adhesiveness for cutaneous wound healing
TL;DR: The antibacterial electroactive injectable hydrogel dressing prolonged the lifespan of dressing relying on self-healing ability and significantly promoted the in vivo wound healing process attributed to its multifunctional properties, meaning that they are excellent candidates for full-thickness skin wound healing.
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Influence of pH on wound-healing: a new perspective for wound-therapy?
TL;DR: The conclusion to be drawn at present is that the wound pH indeed proves to be a potent influential factor for the healing process and that different pH ranges are required for certain distinct phases of wound healing.